Table 4.

Course of chemotherapy according to age groups for 6/8-CHOP-14 + 8xR (RICOVER-60 trial) and CHOP-R-ESC trials

Course of chemotherapy		% of age group				Total
		61–65 years	66–70 years	71–75 years	76–80 years
RICOVER-60 trial 6-CHOP-14 + 8xR	n	90	103	73	40	306
	Regular	82 (91%)	92 (89%)	56 (77%)	26 (65%)	256 (84%)
	Non-regular because of toxicity	2 (2%)	7 (7%)	10 (14%)	13 (33%)	32 (11%)
RICOVER-60 trial 8-CHOP-14 + 8xR	n	108	85	71	40	304
	Regular	83 (77%)	54 (64%)	42 (59%)	12 (30%)	191 (63%)
	Non-regular because of toxicity	17 (16%)	18 (21%)	17 (24%)	22 (55%)	74 (24%)
CHOP-R-ESC trials	n	149	188	141	83	561
	Regular	138 (93%)	173 (92%)	129 (92%)	66 (80%)	506 (90%)
	non-regular because of toxicity	4 (3%)	10 (5%)	9 (6%)	14 (17%)	37 (7%)

Remark: Regular course of chemotherapy means, patient received all planned cycles of chemotherapy. Non-regular course of chemotherapy because of toxicity means, patient received not all planned cycles of chemotherapy due to toxicity