Table 4.
The relationship between NLR and clinico-pathological factors in patients undergoing potentially curative resection for esophageal cancer
| Clinico-pathological factors | NLR low n (%) | NLR high n (%) | p-value |
|---|---|---|---|
| Age (years) | 0.538 | ||
| < 65 | 88 (33.5) | 12 (38.7) | |
| 65–75 | 129 (49.0) | 12 (38.7) | |
| > 75 years | 46 (17.5) | 7 (22.6) | |
| Sex | 0.848 | ||
| Female | 39 (14.8) | 5 (16.1) | |
| Male | 224 (85.2) | 26 (83.9) | |
| T stage | 0.150 | ||
| CR | 17 (6.5) | 5 (16.1) | |
| 1 | 70 (26.6) | 4 (12.9) | |
| 2 | 28 (10.6) | 4 (12.9) | |
| 3 | 127 (48.3) | 17 (54.8) | |
| 4 | 21 (8.0) | 1 (3.2) | |
| N stage | 0.993 | ||
| 0 | 129 (49.0) | 16 (51.6) | |
| 1 | 72 (27.4) | 8 (25.8) | |
| 2 | 43 (16.3) | 5 (16.1) | |
| 3 | 19 (7.2) | 2 (6.5) | |
| Tumour stage | 0.213 | ||
| CR | 17 (6.5) | 5 (16.1) | |
| I | 76 (28.9) | 6 (19.4) | |
| II | 53 (20.2) | 7 (22.6) | |
| III | 117 (44.5) | 13 (41.9) | |
| Differentiation | 0.549 | ||
| Well/moderate | 155 (58.9) | 20 (64.5) | |
| Poor | 108 (41.1) | 11 (35.5) | |
| Vascular invasion | 0.960 | ||
| No | 137 (52.1) | 16 (51.6) | |
| Yes | 126 (47.9) | 15 (48.4) | |
| Lymph node sample | 0.018 | ||
| ≥ 15 | 144 (54.8) | 10 (32.3) | |
| < 15 | 119 (45.2) | 21 (67.7) | |
| R status | 0.466 | ||
| 0 | 162 (61.6) | 17 (54.8) | |
| 1 | 101 (38.4) | 14 (45.2) | |
| Peri-operative chemotherapy | 0.031 | ||
| No | 83 (31.6) | 4 (12.9) | |
| Yes | 180 (68.4) | 27 (87.1) | |
| White cell count | < 0.001 | ||
| Low | 18 (6.8) | 2 (6.5) | |
| Normal | 244 (92.8) | 25 (80.6) | |
| High | 1 (0.4) | 4 (12.9) | |
| Neutrophil count | < 0.001 | ||
| Low | 261 (99.2) | 19 (61.3) | |
| High | 2 (0.8) | 12 (38.7) | |
| Lymphocyte count | < 0.001 | ||
| Low | 24 (9.1) | 20 (64.5) | |
| Normal | 231 (87.8) | 11 (35.5) | |
| High | 8 (3.0) | 0 (0.0) | |
| Platelet count | 0.177 | ||
| Low | 257 (97.7) | 29 (93.5) | |
| High | 6 (2.3) | 2 (6.5) | |
| CRP | < 0.001 | ||
| Normal | 230 (87.5) | 17 (54.8) | |
| High | 33 (12.5) | 14 (45.2) | |
| Albumin | < 0.001 | ||
| Normal | 227 (86.3) | 18 (58.1) | |
| Low | 36 (13.7) | 13 (41.9) | |
| Modified Glasgow Prognostic Score | < 0.001 | ||
| 0 | 230 (87.5) | 17 (54.8) | |
| 1 | 23 (8.7) | 5 (16.1) | |
| 2 | 10 (3.8) | 9 (29.0) | |
| Neutrophil-Platelet Score | < 0.001 | ||
| Low | 255 (97.0) | 18 (58.1) | |
| Intermediate | 8 (3.0) | 12 (38.7) | |
| High | 0 (0.0) | 1 (3.2) | |
| Platelet-Lymphocyte ratio | < 0.001 | ||
| Low | 136 (51.7) | 1 (3.2) | |
| High | 127 (48.3) | 30 (96.8) |