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. 2021 Mar 2;8:611721. doi: 10.3389/fvets.2021.611721

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Copyright © 2021 Yuan, Yan, Li, Wang, Su and Sun.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Pathological changes and IHC assays of TGEV HQ2016-inoculated piglets. (A,B) H.E staining for jejunum and ileum tissue section of control piglets. (C,D) H.E staining for jejunum and ileum tissue section of TGEV HQ2016 challenged piglets. Villus atrophy, degenerate mucosal epithelial cells, and necrosis. (E,F) IHC assays for jejunum and ileum tissue section of control piglets. (G,H) IHC assays for jejunum and ileum tissue section of TGEV HQ2016 challenged piglets. Positive cells presented in the epithelial cells in the atrophied villi of the segments of jejunal and ileal tissues from the piglets.