Fig. 4.

LiCl promoted autophagy, inhibited apoptosis and osteoclastogenesis during OTM in mice. a, Immunohistochemical staining of Beclin-1 in the tension area of OTM in different groups on day 7 and day 14. b, Immunohistochemical staining of OPG and RANKL in the tension area during OTM in different groups on day 14. c, TUNEL examination of cell apoptosis in the tension side area on day 3. Green fluorescence represents apoptotic cells. d, The MOD of Beclin-1 in the tension area on day 7 and day 14. e, The ratio of OPG/RANKL in the tension area during OTM on day 14. f, Quantification analysis of the apoptotic cells. Data represent means ± S. D (n = 3). (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)