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. 2021 Mar 15;12(3):270. doi: 10.1038/s41419-021-03565-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Cluster analysis of different expressed cirRNAs. Red indicated upregulated while green indicated downregulated. b Scatter plot for circRNA in tumor tissues, adjacent tumor tissues and normal tissues of LNLM1 and LNLM0 patients. c Venny analysis for different expressed in three groups. LNLM1: lymph node negative CRC patients with synchronous liver metastasis; LNLM0: lymph node negative CRC patients without synchronous liver metastasis. T: tumor tissues of LNLM1, P: adjacent tumor tissues of LNLM1, N: normal tissues of LNLM1; T’: tumor tissues of LNLM0, P’: adjacent tumor tissues of LNLM0, N’: normal tissues of LNLM0.