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. 2021 Mar 15;11:5923. doi: 10.1038/s41598-021-85148-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Absolute and relative numbers of monocytes and DCs in healthy controls, stable cirrhosis and in acute decompensation of cirrhosis. A series of comparisons of absolute and relative numbers of monocytes (Panel a) and DCs (Panel b) obtained by manual gating and differences among study groups. *p ≤ 0.05; **p ≤ 0.01. In Panel (a), a and b: difference between SC and CTR and AD and CTR (p ≤ 0.01), α and β: difference between AD and CTR and AD and SC (p ≤ 0.01). AD Acute decompensation of cirrhosis, cDC Classical dendritic cell, cMo Classical monocytes, CTR Healthy controls, DCs Dendritic cells, iMo Intermediate monocytes, ncMo Nonclassical monocytes, pDC Plasmacytoid dendritic cell, SC Stable cirrhosis. Differences were tested using Kruskal–Wallis or ANOVA/Bonferroni. Parametric variables are represented by boxplot with a “ + ” (mean) or by column chart.