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. 2021 Mar 15;11:5923. doi: 10.1038/s41598-021-85148-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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HLA-DR and CD62L expression on monocytes. Panel (a) HLA-DR and CD62L expression on monocytes of healthy controls, stable cirrhosis and in acute decompensation of cirrhosis.Values are represented as MFI of HLA-DR expression and percentage of CD62L⁺ monocytes. Panel (b) Heatmap of the FCS files of 30 CTR, 29 SC and 39 AD merged together. The colors in the heatmap represent the median of the intensity of HLA-DR and CD62L expression on monocytes, varying from black for lower expression to light yellow for higher expression. *p ≤ 0.05; **p ≤ 0.01. AD Acute decompensation of cirrhosis, cMo Classical monocytes, CTR Healthy controls, MFI Mean fluorescence intensity, SC Stable cirrhosis, TiMas Tissular macrophages. Differences were tested using Kruskal–Wallis or ANOVA/Bonferroni. Parametric variables are represented by column chart.