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. 2021 Mar 15;11:5934. doi: 10.1038/s41598-021-85202-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Correlations between neutralizing activity and IgG antibody titer of COVID-19 patients. (A) The correlations between neutralizing antibody titer (ID75) and anti-spike S1 + S2 IgG titer (OD 450 nm, tenfold dilution). (B) The correlations between neutralizing antibody titer (ID75) and anti-spike RBD IgG titer (OD 450 nm, tenfold dilution). OU (left), serum samples collected from patients in the ICU of Osaka University Hospital (n = 12); Ju (right), serum samples collected from patients in Osaka City Juso Hospital (n = 31). The correlation coefficient was calculated by Spearman’s rank correlation test, common logarithmic transformation (X axes). Graphs made in GraphPad Prism version 8.4.3, https://www.graphpad.com/scientific-software/prism/.

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