Fig. 6. PLGA-NB delivery platform can promote scarless wound healing in rabbit and porcine skin wound healing model.
A Representative images of rabbit ear skin wound healing and scar formation in differently treated groups. Left upper panel shows the respective treatment for each wound on the ear. B, C Quantification of collagen deposition and SEI (scar elevation index) at different time points after wounding. n = 4 independent samples. Data are presented as mean ± SD. All error bars represent SD. p values for representative data are shown (One-tailed paired Student’s t-test). D Representative images of porcine skin wound healing and scar formation in differently treated groups. E, F Quantification of collagen deposition and SEI (scar elevation index) at different time points after wounding. n = 5 independent samples. Data are presented as mean ± SD. p values for representative data are shown (One-tailed paired Student’s t-test). All error bars represent SD. Source data are provided as a Source Data file.