Table 1.
Biochemical parameters and Na-K-2Cl cotransporter protein expression.
| Parameter | Groups | ||
|---|---|---|---|
| Control | CLP | CLP + GP | |
| Urea (mg/dL) | 28 ± 1.7 | 52 ± 3.7* | 37 ± 1.2*,† |
| Creatinine (mg/dL) | 0.45 ± 0.05 | 1.22 ± 0.11* | 0.62 ± 0.02† |
| NGAL (ng/mgcreat.) | 0.24 ± 0.05 | 1.43 ± 0.27* | 1.38 ± 0.22* |
| UNa (mEq/mL) | 0.51 ± 0.22 | 1.05 ± 0.51* | 0.64 ± 0.53† |
| UK (mEq/mL) | 0.88 ± 0.17 | 1.47 ± 0.52* | 1.13 ± 0.22† |
| OSMU (mmoL/kg H2O) | 695.4 ± 215.8 | 487.8 ± 204.4* | 873.3 ± 430.7† |
| NKCC2 (%) | 113 ± 23 | 47.22 ± 31* | 83 ± 27.41† |
CLP cecal ligation and puncture, GP green propolis, NGAL neutrophil gelatinase-associated lipocalin, UNa urinary excretion of sodium, UK urinary excretion of potassium, OSMU, urine osmolality, NKCC2 Na-K-2Cl cotransporter.
*p < 0.05 versus control; †p < 0.05 versus CLP.