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. 2021 Mar 15;12(3):274. doi: 10.1038/s41419-021-03546-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Schematic diagram illustrating the construction of expression vectors AAV2-5HRE and AAV2-5HRE-bFGF. B Western blotting analyses of primary NSCs, AAV2-5HRE-NSCs, and AAV2-5HRE-bFGF-NSCs showing the expression of bFGF under normoxic or hypoxic conditions for 24 h. C The quantitative analyses of bFGF protein expression by western blot. D ELISA assay results showing bFGF secretion in primary NSCs, AAV2-5HRE-NSCs, and AAV2-5HRE-bFGF-NSCs under normoxic conditions. E ELISA assay results showing bFGF secretion of primary NSCs, AAV2-5HRE-NSCs, and AAV2-5HRE-bFGF-NSCs under hypoxic conditions. “*” and “**” represents P < 0.05 or P < 0.01 versus normoxia control. Data are the mean values ± SEM.