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. 2021 Mar 15;11:5897. doi: 10.1038/s41598-021-85242-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Tumor xenograft studies after i.v. injections of exosomes. (A) Quantitation of LCP1 mRNA change. (Data are presented as means ± SD. N = 5. *P < 0.05.) (B) Quantitation of LCP1 protein change. A, B. Based on qPCR and Western blot analyses. Note that LCP1 was considerably suppressed in the octExosome group compared to siControl exosome and control groups at both the mRNA level and protein level. (C) Immunohistochemical analysis of tumor LCP1 and PCNA changes. LCP1 and PCNA expressions were considerably suppressed in the octExosome group. Scale bars indicate 50 μm.