Table.

Correlation of Clinicopathological Features with Positive AURKB Expression in RB Patient Specimens

	N	Positive AURKB Expression	Negative AURKB Expression	Statistical Test	P	Significance
Baseline characteristics
Age at diagnosis (mo), n				Student's t-test	0.22	NS
Median	36	36	24
Mean	32.94 ± 22.39	35.25 ± 24.9	26 ± 10.02
Range	2–108	2–108	12–36
Gender, n				χ2 test	0.61	NS
Male	27	21	6
Female	21	15	6
Laterality, n				χ2 test	0.81	NS
Unilateral	41	31	10
Bilateral	7	5	2
Association of histopathological features with AURKB expression
Choroid invasion, n				χ2 test	0.50	NS
Present	24	19	5
Absent	24	17	7
Optic nerve invasion, n				χ2 test	0.01	SS
Present	34	29	5
Absent	14	7	7
Anterior chamber invasion, n				χ2 test	0.04	SS
Present	10	10	0
Absent	38	26	12
Scleral invasion, n				χ2 test	0.83	NS
Present	9	7	2
Absent	39	29	10

P < 0.05 represents statistical significance. SS, statistical significance; NS, no significance.