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. 2021 Mar 2;9:623701. doi: 10.3389/fbioe.2021.623701

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Copyright © 2021 Théatre, Cano-Prieto, Bartolini, Laurin, Deleu, Niehren, Fida, Gerbinet, Alanjary, Medema, Léonard, Lins, Arabolaza, Gramajo, Gross and Jacques.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Top: The surfactin biosynthetic gene cluster. Structural NRPS genes are indicated in red. The regulatory gene comS, which is co-encoded in SrfAB is indicated in purple. Bottom: Classic module and domain architecture of SrfAA-SrfAD.