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. 2021 Mar 2;12:617951. doi: 10.3389/fimmu.2021.617951

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Copyright © 2021 Rogier, Nace, Dimbu, Wakeman, Pohl, Beeson, Drakeley, Tetteh and Plucinski.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Distribution of the five post-treatment clearance parameters by Ig isotype/subclass for antibodies to malaria antigens in Angolan children treated for Plasmodium falciparum malaria. Violin plots display data for all P. falciparum antigens with the median estimate as a white point, black bars as the interquartile range (IQR), and whiskers extending 1.5 × IQR. Plots occasionally do not exist for IgG₂ and/or IgG₄ as not enough children samples provided quantifiable assay signals for these subclasses. Statistical comparison among isotypes shown in Supplementary Table 2. MFI-bg: median fluorescence intensity minus background assay signal.