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. 2021 Mar 2;15:643871. doi: 10.3389/fnins.2021.643871

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Copyright © 2021 Luppi, Spindler, Menon and Stamatakis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Anticorrelations in the human brain. (A) Surface projection of the default mode network (red) and fronto-parietal (blue)/dorsal attention networks (cyan) onto medial and lateral surfaces of a standard brain (left hemisphere). (B) The timecourses of default mode and fronto-parietal networks are anti-correlated during quiet wakefulness. (C) Anticorrelations are reduced or even abolished in the anaesthetised brain. Data from one representative subject, before and during propofol anaesthesia; for experimental details, see Stamatakis et al. (2010) and Varley et al. (2020).