Table 1.
Baseline demographics.
| OVERALL n = 408 | WITHOUT MAD n = 376 | WITH MAD n = 32 | ||
|---|---|---|---|---|
| Median (Interquartile Range) | Median (Interquartile Range) | Median (Interquartile Range) | p-value | |
| Age (years) | 82 (78–85) | 82 (78–85) | 82 (78–87) | 0.76 |
| Body mass index (kg/m2) | 26.4 (23.9–29.7) | 26.4 (23.9–29.9) | 24.8 (23.6–28.3) | 0.14 |
| Body surface area (m2) | 1.81 (1.7–1.99) | 1.81 (1.70–1.97) | 1.83 (1.65–2.00) | 0.81 |
| EuroSCORE II | 4.0 (2.3–8.0) | 4.2 (2.3–8.1) | 3.0 (2.0–5.0) | 0.056 |
| Mean (Standard deviation) | Mean (Standard deviation) | Mean (Standard deviation) | p-value | |
| Weight (kg) | 74 (±14) | 74 (±14) | 73 (±15) | 0.65 |
| Height (cm) | 165 (±9) | 165 (±10) | 167 (±9) | 0.30 |
| Count (Percentage) | Count (Percentage) | Count (Percentage) | p-value | |
| Females | 192 (47 %) | 176 (47 %) | 16 (50 %) | 0.85 |
| NYHA III or IV | 156 (38 %) | 141 (38 %) | 15 (47 %) | 0.34 |
| Arterial hypertension | 337 (83 %) | 309 (82 %) | 28 (88 %) | 0.63 |
| Diabetes | 109 (27 %) | 101 (27 %) | 8 (25 %) | 1.0 |
| Current/Previous smokers | 165 (40 %) | 150 (40 %) | 15 (47 %) | 0.46 |
| Dyslipidaemia | 274 (67 %) | 248 (66 %) | 26 (81 %) | 0.081 |
| Chronic obstructive pulmonary disease | 63 (15 %) | 59 (16 %) | 4 (13 %) | 0.80 |
| Clinically relevant coronary artery disease | 230 (56 %) | 215 (57 %) | 15 (47 %) | 0.27 |
| Previous cardiovascular interventions | 98 (24 %) | 87 (23 %) | 11 (34 %) | 0.19 |
| Cerebrovascular disease | 80 (20 %) | 87 (23 %) | 3 (9 %) | 0.17 |
| Peripheral artery disease | 86 (21 %) | 79 (21 %) | 7 (22 %) | 1.0 |
| Moderate/ severe mitral regurgitation | 107 (26 %) | 99 (26 %) | 8 (25 %) | 1.0 |
| Severe mitral annular calcification | 100 (25 %) | 85 (24 %) | 15 (27 %) | 0.29 |
| Mitral valve prolapse | 12 (3 %) | 6 (2 %) | 6 (19 %) | <0.001 |
Abbreviations: EuroSCORE, European System for Cardiac Operative Risk Evaluation; NYHA, New York Heart Association.