Fig. 4.

Time trends of pooled Helicobacter pylori eradication rates of standard triple therapy from randomized controlled trials performed in Korea (by years). The overall eradication rates of standard triple therapy were 71.6% (95% confidence interval [CI], 69.9% to 73.3%) in ITT analysis and 79.6% (95% CI, 76.6% to 82.2%) in PP analysis. The eradication rates from 2007 to 2011 were 72.3% (95% CI, 71.2% to 74.4%) in ITT analysis and 81.5% (95% CI, 79.9% to 82.9%) in PP analysis. The eradication rates from 2012 to 2016 were 70.3% (95% CI, 68.4% to 72.1%) in ITT analysis and 77.4% (95% CI, 75.6% to 79.2%) in PP analysis.

ITT, intention-to-treat; PP, per protocol. *p<0.01.