Table 4.
Regimen of Recommended Therapies for Helicobacter pylori Infection
| Regimen | Drugs | Frequency | Duration (day) |
|---|---|---|---|
| Standard triple therapy | PPI (standard dose) | bid | 7–14 |
| Clarithromycin (500 mg) | |||
| Amoxicillin (1 g) | |||
| Bismuth quadruple | PPI (standard dose) | bid | 10–14 |
| Bismuth subcitrate (120 mg) | qid | ||
| Tetracycline (500 mg) | qid | ||
| Metronidazole (500 mg) | tid | ||
| Sequential | PPI (standard dose) + amoxicillin (1 g) then, PPI + clarithromycin + metronidazole | bid | 5 |
| bid | 5 | ||
| Concomitant | PPI (standard dose) | bid | 10 |
| Clarithromycin (500 mg) | |||
| Amoxicillin (1 g) | |||
| Metronidazole (500 mg) | |||
| Hybrid | PPI (standard dose) + amoxicillin (1 g) then, PPI + amoxicillin + clarithromycin + metronidazole | bid | 7 |
| bid | 7 | ||
| Levofloxacin triple | PPI (standard dose) | bid | 10–14 |
| Levofloxacin (500 mg or 250 mg) | qd (500 mg), bid (250 mg) | ||
| Amoxicillin (1 g) | bid |
PPI, proton pump inhibitor; qd, once a day; bid, twice per day; tid, three times per day; qid, four times per day.