Statement 8. Eradication rates of bismuth quadruple therapy (standard dose PPI twice daily, metronidazole 500 mg three times daily, bismuth 120 mg and tetracycline 500 mg four times daily for 10 to 14 days) are similar to 14 days standard triple therapy, 10 days CT, and 10 days sequential therapy. However, because of its high adverse effects and potential use as second-line therapy, it can be recommended to be used as first-line therapy if other first-line therapy options are not available.

Grade of recommendation: weak

Level of evidence: moderate

Experts’ opinions: completely agree (50.0%), mostly agree (33.4%), partially agree (10.0%), mostly disagree (3.3%), completely disagree (3.3%), not sure (0%)