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. 2021 Jan 22;15(2):168–195. doi: 10.5009/gnl20288
Statement 9. After failure of standard triple therapy, a bismuths quadruple therapy (PPI, bismuth, tetracycline, and metronidazole) for 14 days is recommended as a second-line therapy.
Grade of recommendation: strong
Level of evidence: high
Experts’ opinions: completely agree (90.0%), mostly agree (6.7%), partially agree (3.3%), mostly disagree (0%), completely disagree (0%), not sure (0%)