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. 2020 Sep 15;15(2):206–216. doi: 10.5009/gnl20127

Table 3.

Formulas of Noninvasive Fibrosis Marker Panels

Formula Equation
Fibrosis-4 (Age [years]×AST [U/L])/(platelet [109/L]×(ALT [U/L])1/2)
NAFLD fibrosis score –1.675+(0.037×age [years])+(0.094×BMI [kg/m2])+(1.13×IFG or diabetes [yes=1, no=0])
+(0.99×AST/ALT)–(0.013×platelet count [109/L])–(0.66×albumin [g/dL])
APRI ([AST/upper limit of normal]/platelet count [109/L])×100

AST, aspartate aminotransferase; ALT, alanine transferase; NAFLD, nonalcoholic fatty liver disease; BMI, body mass index; IFG, impaired fasting glucose; APRI, AST to platelet ratio index.