Table 3.

The efficacy of Rec-ELISA using rNP, rMLD, and rNP/rMLD for the detection of anti-CCHFV IgG antibodies in sera of acute and convalescent CCHF patients

	Rec-ELISA using
	rMLD	rNP	rNP/rMLD
Acute CCHF (day 1–day 7)
Sensitivity	69% (56–79)	72% (59–82)	73% (61–84)
Specificity	98% (88–100)	98% (88–100)	98% (89–100)
Positive predictive value (PPV)	98% (88–100)	98% (89–100)	98% (89 -100)
Negative predictive value (NPV)	68% (55–79)	70% (57–81)	71% (58–82)
Likelihood ratio	29.6%	30.9%	31.6%
Convalescent CCHF (day 8–25)
Sensitivity	89% (73–97)	97% (85–100)	97% (85–100)
Specificity	98% (88–100)	98% (88–100)	98% (88–100)
Positive predictive value (PPV)	97% (84–100)	97% (85–100)	97% (85–100)
Negative predictive value (NPV)	91% (79–98)	98% (88–100)	98% (88–100)
Likelihood ratio	38.1%	41.8%	41.8%

Except for Likelihood ratio, data presented as percent (95% confidence Interval).