Table 3.

Effects of triple agonist application and cholinergic agonist treatment on Aβ-induced reduction of AMPA receptor surface expression

	Normalized ratio of surface/input levels
GluA1
sAβ42	1.00
sAβ42+NS-3861+PNU-282987+RJR-2403 Oxalate	0.85 ± 0.33
sAβ42+Carbachol	0.6 ± 0.19
oAβ42	0.54 ± 0.14
oAβ42+NS-3861+PNU-282987+RJR-2403 Oxalate	0.42 ± 0.17
oAβ42+Carbachol	0.38 ± 0.13
GluA2
sAβ42	1.00
sAβ42+NS-3861+PNU-282987+RJR-2403 Oxalate	1.04 ± 0.43
sAβ42+Carbachol	0.78 ± 0.23
oAβ42	0.67 ± 0.29
oAβ42+NS-3861+PNU-282987+RJR-2403 Oxalate	0.58 ± 0.22
oAβ42+Carbachol	0.36 ± 0.16