Mitochondrial localized Sod2 is required for growth at elevated temperatures.A, The indicated strains were serially diluted and spotted onto SC agar plates, incubated at 25 °C, 30 °C, or 37 °C for 3 to 4 days and photographed. B, Same as in (A), but using strains only expressing mitochondrial Sod2 (SOD2mito) or only expressing cytosolic Sod2 (SOD2cyto). SC, synthetic complete; SOD, superoxide dismutase.