Figure 2.

Molecular dynamics model of slow-severing boundary is consistent with cryo-EM data.A, Alignment of actin subunits i-2: i+1 from the final Slow boundary model structure, red and blue, to that from PDB ID 6UC4, semitransparent blue (29), shows good agreement for the structure of the interface, as quantified in Fig. S2. B, This boundary model structure is also consistent with the original ∼9 Å resolution cryo-EM density map (EMDataBank EMD-20726). Here, the same structure in A is shown with the EM map overlaid (semitransparent isosurface), after performing an all-atom alignment of the full MD structure to the density using UCSF Chimera (32).