Table 1.
Study Cohort Demographic and Ocular Measures
| Overall (n = 1604) | KYAMS (n = 297) | The Raine Study (n = 1307) | P Valuea | |
|---|---|---|---|---|
| Ageb yrs (mean ± SD) | 21.1 ± 3.0 | 27.4 ± 1.1 | 20.1 ± 0.1 | <0.001 |
| Male sexc | 784 (48.9%) | 114 (38.4%) | 670 (51.3%) | <0.001 |
| Ethnicityd | 0.39 | |||
| Caucasian | 1373 (85.6%) | 256 (86.2%) | 1117 (85.5%) | |
| East Asian | 32 (2.0%) | 3 (1.0%) | 29 2.2%) | |
| South Asian | 22 (1.4%) | 2 (0.7%) | 20 1.5%) | |
| Other/mixed | 177 (11.0%) | 36 (12.1%) | 141 (10.8%) | |
| Ocular measurese (median [IQR]) | ||||
| BCVA | −0.08 [−0.10 to 0.00] | −0.10 [−0.12 to 0.00] | −0.06 [−0.10 to 0.00] | 0.004 |
| Spherical equivalent (D) | +0.25 [−0.38 to 0.63] | +0.00 [−0.63 to +0.50] | +0.25 [−0.38 to +0.63] | 0.036 |
| Axial length (mm) | 23.5 [23.0 to 24.1] | 23.5 [22.9 to 24.2] | 23.5 [23.0 to 24.1] | 0.28 |
| Corneal radius (mm) | 7.72 [7.56 to 7.90] | 7.68 [7.54 to 7.89] | 7.72 7.56 to 7.90] | 0.11 |
| CCT (µm) | 538 [516 to 560] | 535 [514 to 558] | 539 [517 to 560] | 0.06 |
| IOP (mm Hg) | 15 [13 to 17] | 14 [11 to 16] | 15 [13 to 18] | <0.001 |
BCVA, best-corrected visual acuity; CCT, central corneal thickness; IOP, intraocular pressure; IQR, interquartile range; KYAMS, Kidskin Young Adult Myopia Study; SD, standard deviation.
a
Statistical significance set at P < 0.05.
b
Cohort difference analyzed using independent sample t-test.
c
Cohort difference analyzed using χ2 test.
d
Cohort difference analyzed using Fisher's exact test.
e
Cohort difference analyzed using generalized estimating equations.