Table 2.

Association Between 24-Hour Norepinephrine Levels and Blood Pressure in Males with Obstructive Sleep Apnea

	Overall*				Normal-Weight†			Overweight/Obesity†
	B	β	p	Interaction p‡	B	β	p	B	β	p
SBP (mm Hg)
24-hour urinary norepinephrine (ug)	0.093	0.157	0.082	0.009	0.277	0.454	0.012	0.007	0.012	0.909
DBP (mm Hg)
24-hour urinary norepinephrine (ug)	0.096	0.212	0.023	0.140	0.182	0.399	0.041	0.060	0.133	0.223
MAP (mm Hg)
24-hour urinary norepinephrine (ug)	0.095	0.198	0.032	0.046	0.213	0.432	0.023	0.042	0.089	0.407

Notes: *The linear regression models in overall samples were adjusted for age, overweight/obesity, antihypertensive medications use, minimum oxygen saturation, Epworth Sleepiness Scale scores, and percentage of non-rapid eye movement sleep stage 2. ^†The linear regression models in normal weight and overweight patients with OSA were adjusted for age, antihypertensive medications use, minimum oxygen saturation, Epworth Sleepiness Scale scores, and percentage of non-rapid eye movement sleep stage 2. ^‡The p values of interaction between 24-hour urinary norepinephrine and overweight/obesity. Overweight/obesity was defined as a body mass index≥25 kg/m².

Abbreviations: B, unstandardized coefficients; β, standardized coefficients; DBP, diastolic blood pressure; MAP, mean arterial pressure; SBP, systolic blood pressure.