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. 2020 Nov 7;11(1):150–162. doi: 10.34172/apb.2021.016

Table 5. Release Kinetics of in-situ gelling formulations .

Code Zero order First order Matrix Korsmeyer-Peppas Hixson Crowell
R 2 R 2 R 2 K R 2 n R 2
CBZ NLC dispersion 0.9814 0.9906 0.9700 18.89 0.9920 0.6834 0.9919
CBZ in-situ gel 0.9797 0.9920 0.9732 12.35 0.9936 0.6812 0.9892
CBZ NLC in-situ gel 0.9835 0.9861 0.9497 14.76 0.9540 0.6131 0.9875

Note. CBZ: Carbamazepine, NLC: Nanostructured lipid carriers, K is Higuchi constant and n value in Korsmeyer-Peppas indicates mechanism of drug release