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The effect of curcumin and its analogues on HER2 expression in MCF-7/HER2 cells. Cells were treated with ½ IC50 value of each of the single compound and its combination with doxorubicin for 16 h and then analyzed by immunofluorescence. A. Untreated cells with antibody HER2; cells treated with B. Doxorubicin, C. Curcumin, D. Curcumin+Doxorubicin, E. PGV-0, F. PGV-0+doxorubicin, G. PGV-1, and H. PGV-1+doxorubicin. Arrows indicate the localization of HER2
