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. 2021 Mar 6;26(5):1424. doi: 10.3390/molecules26051424

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Inhibitory effects of RF on neuropeptide-induced macrophage activation in UVB-exposed mice skin and UVB- or heat-treated sensory neuronal cells. (A,B) The CD163 expression level was analyzed by immunohistochemistry. Scale bar = 100 µm; (3 mice per group) (C) The cell experimental scheme for Raw264.7. affected by F11 cells; (D,E) mRNA expression of the Cd163 by qRT-PCR in UVB-CM exposure Raw264.7 cell model (D) and heat-CM exposure Raw264.7 cell model (E) and were normalized to that of Actb and expressed relative to the control group. * p < 0.05 vs. Control; ^$ p < 0.05 vs. UVB-CM or Heat-CM; ^# p < 0.05 vs. RF 50 ms.