BM	Bacterial meningitis
CNS	Central nervous system
BBB	Blood-brain barrier
GBS	Group B Streptococcus
HIV	Human immunodeficiency virus
CM	Cryptococcal meningitis
HiB	Haemophilus influenzae
MIC	Minimum inhibitory concentration
TNF-α	Tumor necrosis factor-α
TLR	Toll-like receptors
IL-1α	Interleukin-1α
NLRs	Nod-like receptors
LPS	Lipopolysaccharides
PAMPs	Pathogen-associated molecular patterns
NF-κ B	Nuclear factor kappa B
MAPK	Mitogen-activation protein kinase
PBN	Phenyl N-t-butylnitrone
4-HNE	4-Hydroxynonenal
MDA	Malondialdehyde
iNOS	inducible Nitric Oxide Synthase
HBMEC	Human Brain Microvascular Endothelial Cell
IL-6	Interleukin-6
ROS	Reactive oxygen species
RNS	Reactive nitrogen species
MMPs	Matrix metalloproteinases
CSF	Cerebrospinal fluid
BMECs	Brain microvascular endothelial cells
AJs	Adherens junctions
TJs	Tight junctions
ZO-1	Zonula occluding-1
CSF	Cerebrospinal fluid
SOD	Superoxide dismutase
PMN	Polymorphonuclear
mTOR	Mammalian target of rapamycin
Bmal 1	Brain and muscle Arnt-like protein 1
FAK	Focal Adhesion Kinase
LP	Lactate/pyruvate
MyD88	Myeloid differentiation factor 88
ERK1/2	Extracellular signal-related kinases 1/2
EGFR	Epidermal growth factor receptor
AFMK	N1-acetyl-N2-formyl-5-methoxykynuramine
PCV	Pneumococcal conjugate vaccines
PPV	Pneumococcal polysaccharide vaccine
PspA	Pneumococcal surface protein
Ply	Pneumolysin