. 2021 Mar 5;22(5):2628. doi: 10.3390/ijms22052628

Table 3.

Overview of statistical methods and results of the analyzed studies.

Author, Year	Statistical Method(s)	Survival Outcome(s)	HR, 95% CI	p Value
Kichenadasse, 2020	Cox proportional hazards regression models	PFS	0.88 (0.78–0.99)	0.03
Kichenadasse, 2020	Cox proportional hazards regression models	OS	0.64 (0.51–0.81)	<0.001
Rutkowski, 2020	Cox proportional hazards regression models	PFS	1.00 (0.98–1.03)	0.732
Rutkowski, 2020	Cox proportional hazards regression models	OS	1.02 (0.99–1.05)	0.202
Johannet, 2020	Cox proportional hazards regression models	PFS	1.01 (0.99–1.03)	0.33
Johannet, 2020	Cox proportional hazards regression models	OS	0.99 (0.96–1.02)	0.38
Young, 2020	Log-rank test	PFS	1.28 (0.90–1.83)	0.18
Young, 2020	Log-rank test	OS	1.10 (0.72–1.67)	0.65
Takada, 2020	Cox proportional hazards regression models	PFS	1.47 (1.04–2.05) *	0.0269 *
Takada, 2020	Cox proportional hazards regression models	OS	1.59 (1.10–2.30) *	0.0138 *
Cortellini, 2020	Cox proportional hazards regression models	PFS	0.61 (0.45–0.82)	0.0012
Cortellini, 2020	Cox proportional hazards regression models	OS	0.70 (0.49–0.99)	0.0474
Cortellini, 2020	Log-rank test	PFS	NA	<0.0001
Cortellini, 2020	Log-rank test	OS	NA	<0.0001
Rogado, 2020	Log-rank test	PFS	3.77 (1.33–10.66)	0.01
Martini, 2019	Cox proportional hazards regression models	PFS	0.96 (0.92–1.00)	0.03
Martini, 2019	Cox proportional hazards regression models	OS	0.92 (0.87–0.97)	0.001
Magri, 2019	Cox proportional hazards regression models	OS	1.19 (0.93–1.51)	0.16
Kondo, 2019	Cox proportional hazards regression models	PFS	4.12 (1.84–9.22)	p = 0.001
Popinat, 2019	Cox proportional hazards regression models	OS	0.84 (NA) *	0.007 *
Cortellini, 2019	Cox proportional hazards regression models	PFS	0.46 (0.39–0.54)	<0.0001
Cortellini, 2019	Cox proportional hazards regression models	OS	0.33 (0.28–0.41)	<0.0001
De Giorgi, 2019	Cox proportional hazards regression models	OS	1.58 (1.09–2.28)	0.01
Martini, 2019	Cox proportional hazards regression models	OS	NA ¹	NA ¹
Labadie, 2019	Cox proportional hazards regression models	PFS	0.87 (0.79–0.96)	0.007
Labadie, 2019	Cox proportional hazards regression models	OS	0.19 (0.03–1.11)	0.07
McQuade, 2018	Cox proportional hazards regression models	PFS	0.63 (0.41–0.95)	0.07
McQuade, 2018	Cox proportional hazards regression models	OS	0.54 (0.34–0.86)	0.84
Richtig, 2018	Log-rank test	PFS	1.03 (0.62–1.70)	0.924
Richtig, 2018	Log-rank test	OS	1.81 (0.98–3.33)	0.056

Abbreviations: CI, confidence interval; HR, hazard ratio; NA, not available; OS, overall survival; PFS, progression free survival. * Univariate analysis. ¹ BMI evaluated as a part of the Emory scoring system.