Table 1.
Differences in the expression profiles of microRNAs between malignant and healthy endometrial tissues.
| Reference | Date | Review | Type of Review Article | miRNA Increased | miRNA Decreased | Case Sample | Case Control | Detection Technique |
|---|---|---|---|---|---|---|---|---|
| Wang et al. [27] | 2020 | J Obstet Gynecol Reprod Biol X | Original Article | miR-135a | Human cell lines | Scrambled negative control RNAs | RT-PCR | |
| Wu et al. [28] | 2020 | J Comput Biol | Original Article | miR-449a,-145-5p | Endometrial cancer tissue (n = 77) | Adjacent healthy endometrial tissue (n = 22) | bioinformatics | |
| Donkers et al. [29] | 2020 | Onco target | Literature Review | miR-205, -200c,-223,-182,-183,-200a,-135b,-429,-141,-200b,-200a*,-222,-141-3p,-200c-3p,-186,-200b*,-15b,-106a,-135a,-205-5p,-182-5p,-200b-3p,-92a,-9-5p,-27a,-210,-96,-194, -95,-155,-18a* miR-222-3p miR-96-5p miR-103 miR-151 miR-34a miR-92a-1* miR-887-5p miR-20a* miR-106b* miR-449a miR-17* miR-185 miR-1228 miR-146 miR-425 miR-1290 miR-205 miR-200c miR-223 miR-182 miR-183 miR-200a miR-135b miR-429 miR-141 miR-200b miR-200a* miR-222 miR-141-3p miR-200c-3p miR-186 miR-200b* miR-15b miR-106a miR-135a miR-205-5p miR-182-5p miR-200b-3p miR-92a miR-9-5p miR-27a miR-210 miR-96 miR-194 miR-95 miR-155 miR-18a* miR-222-3p miR-96-5p miR-103 miR-151 miR-34a miR-92a-1* miR-887-5p miR-20a* miR-106b* miR-449a miR-17* miR-185 miR-1228 miR-146 miR-425 miR-1290 | miR-137,-129-3p,-410,-503,-1247,-376c,-377,-26a-5p,-214,-150-5p,-370, let-7f-5p, -26b-5p, let-7c-5p,-23b-3p,-125b-5p, -126-3p, -195-5p, -424-5p, -374a-5p, -let-7a-5p, -let-7e-5p, -125a-5p, -542-5p miR-337-5p miR-1305 miR-758 miR-300 miR-93 miR-125 miR-34 miR-30a-3p miR-301b miR-10b miR-195 miR-30a-5p miR-101 miR-10b* miR-133a miR-133b miR-152 miR-29b miR-34b miR-411 | Endometrial cancer tissue | RT-PCR | |
| Wang et al. [30] | 2020 | Radiol Oncol | Original Article | miR-144-3p | Endometrial cancer Cell lines | RT-PCR | ||
| Liu Y et al. [31] | 2020 | J Cell Mol Med. | Original Article | miR-646 | Endometrial cancer tissue (n = 32) | Normal endometrial tissue (n = 26) | RT-PCR/bioinformatics | |
| Zong et al. [32] | 2020 | J Cell Mol Med | Original Article | miR-136 | Endometrial cancer tissue (n = 69) | RT-PCR | ||
| Zhang et al. [33] | 2020 | Oncol rep | Original Article | miR-320a, miR-340-5p | Endometrial cancer tissue (n = 8) | Adjacent healthy endometrial tissue | RT-PCR | |
| Shi et al. [34] | 2020 | Biochem | Original Article | miR-6076 | Endometrial cancer Cell lines | RT-PCR | ||
| Zhang et al. [35] | 2020 | Exp Cell Res | Original Article | miR-320a | Endometrial cancer tissue (n = 41) | Normal endometrial tissue (n = 7) | bioinformatics | |
| Xin et al. [36] | 2020 | Am J Transl Res | Original Article | miR-205-5p | Endometrial cancer tissue (n = 42) | Normal endometrial tissue (n = 29) | RT-PCR | |
| Wang et al. [37] | 2020 | Oncol Rep | Original Article | miR-21-5p | Endometrial cancer tissue (n = 160) | Adjacent healthy endometrial tissue | RT-PCR | |
| Sato et al. [38] | 2020 | Tohoku J Exp Med | Original Article | miR Let-7c | Paclitaxel-resistant cell lines | RT-PCR | ||
| Dou et al. [39] | 2020 | Kaohsiung J Med Sci | Original Article | miR-335 | Endometrial cancer tissue (n = 47) | Adjacent healthy endometrial tissue | RT-PCR | |
| Wilczynski et al. [40] | 2020 | Acta Obstet Gynecol Scand | Original Article | miRNA-204, miRNA-424 | Endometrioid cancer tissue with lymphadenectomy positive | Endometrioid cancer tissue with lymphadenectomy negative | RT-PCR | |
| Xu et al. [41] | 2020 | Cancer Biother Radiopharm | Original Article | miR-202-3p | Endometrial cancer type 2 (n = 20) | RT-PCR | ||
| Zhao et al. [42] | 2020 | J Cell Biochem | Original Article | miR-31,−205, −211,−425 | Endometrial cancer tissue (n = 546) | Normal endometrial tissue (n = 33) | bioinformatics TCGA | |
| Wang et al. [43] | 2020 | DNA Cell Biol | Original Article | hsa-miR-184,-4461 | hsa-miR-6511b | Endometrial cancer tissue with recurrence (n = 232) | Endometrial cancer tissue with no recurrence (n = 231) | RT-PCR |
| Yang et al. [44] | 2020 | Cell Cycle | Original Article | miR-516b | Endometrial cancer tissue (n = 106) | RT-PCR | ||
| Wang et al. [45] | 2020 | J Cell Mol Med | Original Article | hsa-miR-183-3p, -200b-3p, -429, -1307-3p,-183-5p | miR-542-3p,-152-3p,-24-1-5p,-374b-5p | Endometrial cancer tissue (n = 441) | Normal endometrial tissue | bioinformatics (TCGA) |
| Liu et al. [46] | 2020 | Gene | Original Article | miR-149-5p | Endometrial cancer Cell lines | RT-PCR | ||
| Jia et al. [47] | 2020 | Cancer Cell International | Original Article | miR-182 | Endometrial cancer tissue (n = 50) | Normal endometrial tissue (n = 30) | RT-PCR | |
| Li et al. [48] | 2019 | Oncol Lett | Original Article | miR-23a | Endometrial cancer tissue (n = 16) | Adjacent healthy endometrial tissue | RT-PCR/immunohistochimie | |
| Huang et al. [49] | 2019 | IUBMB | Original Article | miR-146b-5p | Endometrial cancer tissue with progesterone (n = 3) and without progesterone (n = 3) | RT PCR/bio informatics | ||
| Van Sinderen et al. [50] | 2019 | oncol Lett | Original Article | miR-29c | Endometrioid endometrial cancers tissue (n = 35) | Adjacent healthy endometrial tissue | RT-PCR | |
| Hutt S et al. [51] | 2019 | Acta Oncologica | Literature Review | miR-944,-301 | miR-205, -106b | Endometrial cancer tissue | ||
| Li B et al. [52] | 2019 | J Cell Physio | Original Article | miR-148b | Endometrial cancer tissue and cell lines | Adjacent healthy endometrial tissue | RT-PCR | |
| Li Z et al. [53] | 2019 | Molecular and Cellular Biochemistry | Original Article | miR-142-3p | Endometrial cancer tissue (n = 69) | Adjacent healthy endometrial tissue (n = 20) | RT-PCR | |
| Wu et al. [54] | 2019 | Exp cell Res | Original Article | miR-449a | Endometrioid cancer tissue (n = 87) | Different cell lines | RT-PCR/immunohistochimie | |
| Du et al. [55] | 2019 | int J Immunopathol Pharmacol | Original Article | miR-103 | Endometrial cancer tissue (n = 14) | RT-PCR | ||
| Zhu et al. [56] | 2019 | cell Cycle | Original Article | miR-20b-5p | Endometrial cancer tissue (n = 36) | Adjacent healthy endometrial tissue | RT-PCR | |
| Penolazzi L et al. [57] | 2019 | Gene | Original Article | miR-221 | Endometrioid cancer tissue (n = 53), 2 groups: obese patient BMI >30kg/m2 and non obese patient BMI <30kg/m2 | RT-PCR/immunohistochimie | ||
| Hu et al. [58] | 2019 | J cancer | Original Article | miR-449a | Endometrial cancer tissue (n = 40) | Endometrial cancer stage I-II | RT-PCR | |
| liu et al. [59] | 2019 | oncol Lett | Original Article | hsa-miR-200b, -205, -200a, -141, -200c | hsa-miR-503,-876-3p, -144, -133a, -154 | Endometrial cancer tissue (n = 552) | Normal endometrial tissue (n = 23) | RT-PCR/bioinformatics |
| Guo S et al. [60] | 2019 | Pathol Res Pract | Original Article | miR-204-5p | Endometrial cancer tissue (n = 22) | Adjacent healthy endometrial tissue | RT-PCR/bioinformatics (TCGA) | |
| Liu L et al. [61] | 2019 | Acta Biochim Biophys Sin | Original Article | miR-27b-3p | Endometrial cancer tissue (n = 66) | RT-PCR/immunohistochimie | ||
| Xu et al. [62] | 2019 | Gynecol Oncol | Original Article | miR-30c | "Endometrial cancer tissue (n = 161): 141 endometrioid adenocarcinoma, 16 serous adenocarcinoma, and 4 clear cell | Adjacent healthy endometrial tissue | RT-PCR/immunohistochimie | |
| Wang et al. [63] | 2019 | J Cell Biochem | Original Article | hsa-miR-1269a, -205-5p, -4652-5p, -183-3p, -183-5p, -96-5p, -182-5p, -449b-5p, -4724-5p, -891a-5p | Endometrial cancer tissue (n = 91) | Adjacent healthy endometrial tissue | bioinformatics TCGA | |
| Kong et al. [64] | 2019 | J Int Med Res | Original Article | miR-29b | Endometrial cancer Cell lines | RT-PCR | ||
| Kozak et al. [65] | 2019 | Mol Cell Biochem | Original Article | miR-200 family,-141 | Endometrial cancer Cell lines | RT-PCR | ||
| Dong et al. [66] | 2019 | J Exp Clin Cancer Res | Original Article | miR-361 | Endometrial cancer Cell lines | RT-PCR | ||
| Chen P et al. [67] | 2019 | Biosci Rep | Original Article | miR-202 | Endometrial cancer tissue (n = 76) | Adjacent healthy endometrial tissue | RT-PCR | |
| Yi Su et al. [68] | 2019 | DNA Cell Biol. | Original Article | miR-142 | Endometrial cancer tissue (n = 49) | RT-PCR | ||
| Hermyt et al. [69] | 2019 | Int J Mol Sci | Original Article | miR-331-3p, -182,-200c,-155,-200b,-874,-10a,-625,-let-7f,-let-7g,-let-7a-331,331-3p,-15b | miR-370, -432, -1296, -483-5p | Endometrial cancer tissue (n = 40) | Normal endometrial tissue (n = 20) | RT-PCR |
| Zheng et al. [70] | 2019 | Cancer Biother Radiopharm | Original Article | miR-126 | Endometrial cancer tissue (n = 35): 28 endometrioid carcinoma, 3 serous carcinoma, 3 clear cell carcinoma, and 1 undifferentiated carcinoma | Normal endometrial tissue (n = 35) | immunofluorescence assay | |
| X-C Li et al. [71] | 2019 | Eur Rev Med Pharmacol Sci | Original Article | miR-218 | endometrial cancer tissue (n = 25) | Adjacent healthy endometrial tissue | RT-PCR | |
| Asanoma et al. [72] | 2019 | Oncotarget | Original Article | miR-300 family | Endometrial cancer tissue (n = 61); 29 stage IA, 15 stage IB, 1 stage IIA, 1 stage IIB, 2 stage IIIB, 11 stage IIIC, 2 stage IVB; 56 endometrioid cancer, 5 serous carcinoma | Stage 1A endometrioid endometrial cancer (n = 29) | RT-PCR | |
| Fang et al. [73] | 2019 | Onco target | Original Article | miR-214-3p | endometrial cancer tissue (n = 22) | Adjacent healthy endometrial tissue | RT-PCR | |
| Wang et al. [74] | 2019 | pharmazie | Original Article | miR-363 | Endometrial cancer tissue (n = 36) | Normal endometrial tissue (n = 36) | RT-PCR | |
| Deng et al. [75] | 2019 | Mol Med Rep | Original Article | miR-195 | Endometrial cancer Cell lines | RT-PCR | ||
| Gao et al. [76] | 2019 | Int J Nanomedicine | Original Article | miR-326 | Endometrioid endometrial cancer tissue (n = 6) | RT-PCR/bioinformatics | ||
| Wang et al. [77] | 2019 | Cancer Biother Radiopharm | Original Article | miR-589-5p | Endometrial cancer tissue (n = 40) | Adjacent healthy endometrial tissue | RT-PCR | |
| Wu et al. [78] | 2019 | Life Sci | Original Article | miR-616 | Endometrial cancer tissue (n = 120) | Adjacent healthy endometrial tissue | RT-PCR | |
| Zhang et al. [79] | 2019 | Kaohsiung J Med Sci | Original Article | miR-522 | Endometrial cancer Cell lines | RT-PCR/bioinformatics (TCGA) | ||
| Yuan et al. [80] | 2019 | Reprod Sci | Original Article | miR-143,-145 | Endometrial cancer Cell lines | RT-PCR | ||
| Chen et al. [81] | 2019 | Int J Clin Exp Pathol | Original Article | miR-135a | Endometrial cancer Cell lines | RT-PCR | ||
| Tan et al. [82] | 2019 | Pathol Res Pract | Original Article | miR-495 | Endometrial cancer tissue (n = 30) | RT-PCR | ||
| Zhou et al. [83] | 2019 | Biosci Rep | Original Article | miR-940 | Endometrial cancer tissue (n = 546) | Normal endometrial tissue (n = 33) | RT-PCR/bioinformatics (TCGA) | |
| Li et al. [84] | 2019 | Gene | Original Article | miR-29c-3p | Endometrial cancer tissue (n = 80) | Adjacent healthy endometrial tissue | RT-PCR | |
| Zhuang et al. [85] | 2019 | Endocr J | Original Article | miR-181c | Endometrial cancer Cell lines | RT-PCR | ||
| Sun et al. [86] | 2019 | Mol Cell Biochem | Original Article | miR-214 | Endometrial cancer tissue (n = 27) | Normal endometrial tissue (n = 18) | RT-PCR | |
| Shen et al. [87] | 2019 | Cell Cycle | Original Article | miR-197 | Endometrial cancer tissue (n = 36) | RT-PCR | ||
| Zhao et al. [88] | 2019 | J Biosci | Original Article | miR-195 | Endometrial cancer tissue (n = 30) | Normal endometrial tissue (n = 26) | RT-PCR | |
| Liu, Y. et al. [89] | 2018 | Mol. Cell. Biochem | Original Article | miR-181c-3p, -25-5p | miR-99a-3p, -96a-5p, -328-3p, -337-3p, let-7c-5p | Endometrioid endometrial cancer tissue (n = 15) | Adjacent healthy endometrial tissue (n =15) | RT-PCR |
| Liu, Y. et al. [90] | 2018 | Cancer cell Int | Original Article | miR-139-5p | Endometrial cancer tissue (n = 25) | Normal endometrial tissue (n = 15) | RT-PCR | |
| Ma, J. et al. [91] | 2018 | Exp. Clin. Cancer Res | Original Article | miR-302a-5p, -367-3p | Endometrial cancer tissue (n = 80) | Normal endometrial tissue (n = 80) | RT-PCR | |
| Huang et al. [92] | 2018 | Biosci. Rep | Original Article | miR-106b | Endometrial cancer tissue (n = 20) | Normal endometrial tissue (n = 20) | RT-PCR | |
| Fang et al. [93] | 2018 | Cell Biochem. Funct | Original Article | miR-182,-183,-153,-27a,-96 | Endometrial cancer tissue (n = 69); 33N+, 36N− | Normal endometrial tissue (n = 10) | RT-PCR | |
| Ushakov et al. [94] | 2018 | Bull. Exp. Boil. Med | Original Article | miR-29c,-31,-185,-652 | Endometrioid endometrial cancers tissue FIGO I-II (n = 32) | Adjacent healthy endometrial tissue (n =30) | RT-PCR | |
| Xiamei Sun [95] | 2018 | Mol cancer Res | Original Article | miR-652 | Endometrial serous carcinoma (n = 13) endometrioid carcinoma (n = 39) | Normal endometrial tissue (n = 22) | RT-PCR | |
| Yun-Xiao Zhou [96] | 2018 | Int J Biochem Cell Biol | Original Article | miR-146a | Endometrial cancer tissue | Normal endometrial tissue | RT-PCR | |
| Jie Li [97] | 2018 | Exp ther Med | Original Article | miR-423 | Endometrial cancer Cell lines | RT-PCR | ||
| Yan Li [98] | 2018 | J Cell Biochem | Original Article | miR-373 | Endometrial cancer tissue (n = 64) | Adjacent healthy endometrial tissue | RT-PCR | |
| Ying Liu [89] | 2018 | Mol Cell Biochem | Original Article | miR-101 | Endometrial cancer tissue (n = 30) | Adjacent healthy endometrial tissue | RT-PCR | |
| Xiong H [99] | 2018 | J Cell Biochem | Original Article | miR-183 | Endometrial cancer tissue (n = 208) | Adjacent healthy endometrial tissue | RT-PCR | |
| Hua Yan [100] | 2018 | Int J Mol Med | Original Article | miR-185-5p | Endometrial cancer tissue (n = 156) | Adjacent healthy endometrial tissue | RT-PCR | |
| Yu Huang [101] | 2018 | Int J Clin Exp Pathol | Original Article | miR-20a-5p | Endometrial cancer tissue (n = 41) | Adjacent healthy endometrial tissue | RT-PCR | |
| Ruichao Chen [102] | 2018 | Cell Death Dis | Original Article | miR-200c | Endometrial cancer tissue (n = 40) | adjacent healthy endometrial tissue | RT-PCR | |
| Wei Bao [103] | 2018 | Oncol Rep | Original Article | miR-107-5p | Endometrial cancer with lymphadenectomy positive | Endometrial cancer with lymphadenectomy negative | RT-PCR | |
| Li Yang [104] | 2018 | Int J Clin Exp Pathol | Original Article | miR-210 | Endometrial cancer tissue (n = 66);49 stage FIGO I, 7 stage II, 10 stage III | RT-PCR | ||
| Yan et al. [105] | 2018 | Molecular Medicine Reports | Original Article | miR-944 | Endometrial cancer tissue (n = 68); 54 endometrioid, 14 others, 55 FIGO I, 13 FIGO III-IV, 59 n+, 9 n− | Normal endometrial tissue (n = 20) | RT-PCR | |
| Xie et al. [106] | 2017 | Cancer Biomark | Original Article | miR-216b | Endometrioid endometrial cancers tissue (n = 30); 12 FIGO I, 7 FIGO II, 11 FIGO III | Adjacent healthy endometrial tissue (n =30) | RT-PCR | |
| Zhang et al. [107] | 2017 | Cancer Biomark | Original Article | miR-101 | Endometrial cancer tissue (n = 37); 21 FIGO I, 5 FIGO II, 4 FIGO III, 5 FIGO IV | Normal endometrial tissue (n = 22) | RT-PCR | |
| Chen et al. [108] | 2017 | Oncol. Rep | Original Article | miR-5785,-6749-5p,-1202 | miR-338-3p,-449a,-196a | Endometrial cancer tissue (n = 15) | Normal endometrial tissue (n = 15) | RT-PCR |
| Wang Z et al. [109] | 2017 | Oncotarget | Original Article | miR-522, miR-139-3p, miR-520c-5p, miR-518d-5p, miR-146b-5p, miR-34a, miR-526a, miR-193a-3p, miR-221, miR-4674 | miR-760 | Endometrial cancer tissue | Normal endometrial tissue (n = 15) | RT-PCR |
| Liu et al. [110] | 2017 | Cancer biomark | Original Article | miR-1224,-1269,-182,-183, -200b, -205, -219-2, -449a, -891a, -96 | miR-1-2,-100,-101-2,-1247,-133a,-139,-143,-145,-3926-1,-99a | Endometrial cancer tissue (n = 381) | Bioinformatics (TCGA) | |
| Ihira et al. [111] | 2017 | Oncotarget | Original Article | miR-361 | Endometrial cancer cell lines (n = 3), endometrial cancer tissue (n = 24) | RT-PCR | Ihira et al. | |
| Cai et al. [112] | 2016 | Mol. Med. Rep | Original Article | miR-337 | Endometrial cancer tissue (n = 24) | Adjacent healthy endometrial tissue (n =24) | RT-PCR | |
| Zhao et al. [113] | 2016 | Oncol. Lett | Original Article | miR-126 | Endometrial cancer tissue (n = 11) | Adjacent healthy endometrial tissue (n =11) | RT-PCR | |
| Yoneyama et al. [114] | 2015 | Anticancer. Res | Original Article | miR-200a,-200b,-429 | Endometrioid endometrial cancers tissue (n = 7) | Adjacent healthy endometrial tissue (n =7) | RT-PCR | |
| Zhou et al. [115] | 2015 | Drug Des. Dev. Ther | Original Article | miR-181a | Endometrioid endometrial cancers tissue (n = 47); 38 FIGO I-II, 9 FIGO III-IV, 5N+, 42N− | Normal endometrial tissue (n = 13) | RT-PCR | |
| Kong et al. [116] | 2014 | PLoS ONE | Original Article | miR-30c | Endometrioid endometrial cancers tissue (n = 21) | Normal endometrial tissue (n = 14) | RT-PCR | |
| Jurcevic et al. [117] | 2014 | BMC Cancer | Original Article | miR-183, -182, 429, -135a, -9-3p, -9, 135b, -200a-5p, -218, -18a-3p | miR-1247, -199b-5p, -214, -370, -424-3p, -376c, -542-5p, -758, -377, 337-5p | Endometrial cancer tissue (n = 30); 10 FIGO I, 10 FIGO II, 10 FIGO III | Normal endometrial tissue (n = 20) | RT-PCR |
| Tsukamoto et al. [118] | 2014 | Gynecol. Oncol. | Original Article | miR-499, -135b, -205 | miR-10b, -195, -30a-5p, -30a-3p, -21 | Endometrioid endometrial cancers tissue (n = 28); 7 FIGO IA, 4N+, 21 n− | Normal endometrial tissue (n = 14) | RT-PCR |
| Xiong et al. [119] | 2014 | PLoS ONE | Original Article | miR-181c-3p, -25-5p | miR-99a-3p, -96a-5p, -328-3p, -337-3p, let-7c-5p | Endometrioid endometrial cancer tissue (n = 15) | Adjacent healthy endometrial tissue (n =15) | RT-PCR |
| Xu et al. [120] | 2013 | FEBS J. | Original Article | miR-503 | Endometrial cancer tissue (n = 71) | Normal endometrial tissue (n = 5), adjacent healthy endometrial tissue (n = 10) | RT-PCR | |
| Torres et al. [17] | 2013 | Int. J. Cancer | Original Article | miR-9, -141, -183, -200a, -200a*, -200b, -200b*, -200c, -203, -205, -429, -96, -182, -135b | miR-410 | Endometrioid endometrial cancer tissue (n = 77): 50 FIGO I,5 FIGO II,20 FIGO III,2 FIGO IV, 29 n+, 15 n− | Normal endometrial tissue (n = 31) | RT-PCR |
| Torres et al. [121] | 2012 | BMC Cancer | Original Article | miR-99a, -100, -199b | Endometrioid endometrial cancer tissue (n = 77): 50 FIGO I,5 FIGO II,20 FIGO III,2 FIGO, 29 n+, 15 n− | Normal endometrial tissue (n = 31) | RT-PCR | |
| Lee et al. [122] | 2012 | Mod. Pathol. | Original Article | miR-182, -183, -200a, -200c, -205 | Endometrial cancer tissue (n = 22): 15 FIGO IA, 5 FIGO IB, 2 FIGO IIIC1 | Normal endometrial tissue (n = 10) | RT-PCR | |
| Karaayvaz et al. [123] | 2012 | PLoS ONE | Original Article | miR-200c, -205 | Endometrial cancer tissue (n = 48); 24 endometrioid, 13 serous, 5 clear cell, 6 others | Adjacent healthy endometrial tissue (n =48) | RT-PCR | |
| Zhao et al. [124] | 2012 | Plos One | Original Article | miR-106b-93-25 | Endometrial cancer Cell lines | RT-PCR | ||
| Snowdown et al. [125] | 2011 | PLoS ONE | Original Article | miR-9/-9*, -18a, -96, -141, -146a, -200a/b/b*/c, -203, -205, -210, -421, -429, -516a-5p, -605, -614, -936 | miR-10b*, -23a*, -100, -127-3p, -152, -199b-3p, -199b-5p, -370, 376a/c, -381, -410, -424, -424*, -431, -432, -503, -542-3/5p, -596,-610, -630, -632, -760 | Endometrioid endometrial cancer tissue (n = 19); 9 FIGO IA, 4 FIGO IB, 1 FIGO II | Normal endometrial tissue (n = 10) | RT-PCR |
| Cohn et al. [126] | 2010 | Am. J. Obstet. Gynecol | Original Article | miR-9, -19b; -146, -181c, -183, -200c, -205, -223, -423, -425 | let-7a, miR-32, -33b, -369, -409, -424, -431, -451, -496, -503, -516 | Endometrial cancer tissue (n = 141); 121 endometrioid FIGO I, 3 endometrioid FIGO III, 7 serous FIGO III, 4 endometrioid FIGO IV, 6 serous FIGO IV | Normal endometrial tissue (n = 20) | RT-PCR |
| Ratner et al. [127] | 2010 | Gynecol. Oncol | Original Article | miR-182, -183, -200a, -205, -34a, -572, -622, -650 | miR-411, -487b | Endometrioid endometrial cancer tissue (n = 30); 27 serous, 6 carcinosarcoma, 27 FIGO I, 12 FIGO II, 18 FIGO III | Normal endometrial tissue (n = 5) | RT-PCR |
| Chung et al. [128] | 2009 | Int. J. Cancer | Original Article | miR-10a, -17-5p, -23a*, -25, -28, -34a, -95, -103, -106a, -107, -130b, -141, -151, -155, -182, -183, -184, -191, -194, -200a/c, -203, -205, -210, -215, -223, -301, -325, -326, -330 | Endometrioid endometrial cancer tissue (n = 30); 25 FIGO I–II, 5 FIGO III, 3 n+, 27 n− | Normal endometrial tissue (n = 22) | RT-PCR | |
| Wu et al. [129] | 2009 | Eur. J. Cancer Prev | Original Article | miR-200c, -449, -205, -182, -429, -200b, -96, -31, -141, -200a, -363, -210, -432, -203, -10a, -155, -142-5p | miR-204, -193a, -368, -133b, -193b, -99b | Endometrioid endometrial cancer tissue (n = 10); 5 FIGO I, 5 FIGO II | Adjacent healthy endometrial tissue (n =10) | RT-PCR |
| Boren et al. [130] | 2008 | Gynecol. Onco | Original Article | let-7c, miR-103,-106a,-107,-181a,-185,-210,-423 | let-7i, miR-30c,-152,-193,-221 | Endometrioid endometrial cancer tissue (n = 37) | Normal endometrial tissue (n = 20) | RT-PCR |
FIGO: International Federation of Gynecology and Obstetrics, n: ganglionic status, RT-PCR: real-time polymerase chain reaction.