Table A1.
MicroRNAs Regulation of epigenetic modifiers in endometrial cancer.
| miR | Increased Expression level in Endometrial Cancer | Decreased Expression Level in Endometrial Cancer | Methylation Modified | Reference |
|---|---|---|---|---|
| miR-1 | X | [169] | ||
| miR-1-1 | X | [137] | ||
| miR-1-2 | X | [110] | ||
| miR-6 | X | [168] | ||
| miR-7 | X | [169] | ||
| let-7a | X | [29] | ||
| let-7c | X | [29] | ||
| let-7f | X | [29] | ||
| let-7g | X | [29] | ||
| miR-9 | X | [117,121,125,126] | ||
| miR-9* | X | [125] | ||
| miR-9-3p | X | [117] | ||
| miR-10a | X | [128,129,169] | ||
| miR-10b* | X | [125,169] | ||
| miR-10b | X | X | [118] | |
| miR-15a | X | [47,170] | ||
| miR-15b | X | [25,29] | ||
| miR-17 | X | [136] | ||
| miR-17-5p | X | [128] | ||
| miR-18a | X | [125,136] | ||
| miR-18a-3p | X | [117] | ||
| miR-18b | X | X | [137,169] | |
| miR-19b | X | [126] | ||
| miR-20a-5p | X | [101] | ||
| miR-20b-5p | X | [56] | ||
| miR-21 | X | [118] | ||
| miR-21-5p | X | [27] | ||
| miR-23a | X | [128] | ||
| miR-23a* | X | X | [125,169] | |
| miR-23b | X | [169] | ||
| miR-23b-5p | X | [17] | ||
| miR-23c | X | [17] | ||
| miR-24-1* | X | [169] | ||
| miR-25 | X | [128] | ||
| miR-25p | X | [142] | ||
| miR-26a | X | [126] | ||
| miR-26a1 | X | [126] | ||
| miR-27a | X | [171,172] | ||
| miR-27b | X | [136] | ||
| miR-27b-3p | X | [89] | ||
| miR-28 | X | [128] | ||
| miR-29b | X | [169] | ||
| miR-29c | X | [50] | ||
| miR-29c-3p | X | [48] | ||
| miR-30a-5p | X | [118] | ||
| miR-30a-3p | X | [134] | ||
| miR-30c | X | [116,130,173] | ||
| miR-30c2* | X | [169] | ||
| miR-30d | X | X | [139] | |
| miR-31 | X | X | [129,169] | |
| miR-32 | X | [126] | ||
| miR-33a | X | [169] | ||
| miR-33b | X | [128] | ||
| miR-33b* | X | [169] | ||
| miR-34a | X | X | [109,127,128] | |
| miR-34b | X | X | [136] | |
| miR-34b* | X | [169] | ||
| miR-34c | X | [140,174] | ||
| miR-34c-3p | X | X | [169] | |
| miR-34c-5p | X | [169] | ||
| miR-95 | X | [128,169] | ||
| miR-96 | X | [121,125,129,169] | ||
| miR-98 | X | [12] | ||
| miR-99a | X | [121,143] | ||
| miR-99a-3p | X | [119] | ||
| miR-99b | X | [129] | ||
| miR-100 | X | [121,125] | ||
| miR-101 | X | [169] | ||
| miR-101-2 | X | [110] | ||
| miR-103 | X | [128,130] | ||
| miR-106a | X | [29,128,130,136] | ||
| miR-106b | X | [92,175] | ||
| miR-106b-93-25 | X | [124] | ||
| miR-107 | X | [128,130,176] | ||
| miR-107-5p | X | [103] | ||
| miR-123 | X | [126] | ||
| miR-124a-1 | X | X | [137] | |
| miR-124a-2 | X | X | [137] | |
| miR-124a-3 | X | [137] | ||
| miR-125a-3p | X | [169] | ||
| miR-125b-1 | X | [126] | ||
| miR-125b-2 | X | X | [177] | |
| miR-126 | X | [113] | ||
| miR-127-3p | X | [125,169] | ||
| miR-129-2 | X | X | [138] | |
| miR-129-3p | X | [25] | ||
| miR-129-5p | X | [169] | ||
| miR-130a | X | [135] | ||
| miR-130b | X | X | X | [128] |
| miR-132* | X | [169] | ||
| miR-133a | X | X | [25,169] | |
| miR-133b | X | [129,169,177] | ||
| miR-134 | X | [169] | ||
| miR-135a* | X | [29,169] | ||
| miR-135a | X | [117,177] | ||
| miR-135b | X | [29,117,118,121,169,177,178] | ||
| miR-136 | X | [169] | ||
| miR-136* | X | [169] | ||
| miR-137 | X | X | [23,25] | |
| miR-139 | X | [110] | ||
| miR-139-3p | X | [161] | ||
| miR-139-5p | X | [90,169] | ||
| miR-140-3p | X | [169] | ||
| miR-140-5p | X | [169] | ||
| miR-141 | X | [29,121,125,128,178] | ||
| miR-142 | X | [68] | ||
| miR-142-3p | X | X | [136] | |
| miR-142-5p | X | X | [129,177] | |
| miR-143 | X | X | [161,169] | |
| miR-143* | X | [169] | ||
| miR-145 | X | [161,169] | ||
| miR-145* | X | [169] | ||
| miR-145a | X | [126] | ||
| miR-146 | X | [126] | ||
| miR-146a | X | X | [126] | |
| miR-148a | X | [137,173] | ||
| miR-148a-3p | X | [169] | ||
| miR-148b | X | [52] | ||
| miR-150* | X | [136] | ||
| miR-151 | X | [128] | ||
| miR-152 | X | X | [21,125,130,137,169] | |
| miR-153 | X | [100] | ||
| miR-155 | X | [128,129,175] | ||
| miR-181a | X | [12,115,130] | ||
| miR-181c | X | [126] | ||
| miR-181c-3p | X | [119] | ||
| miR-182 | X | X | [25,29,121,122,127,128,129,169,178] | |
| miR-183 | X | [29,122,126,127,128,169,178] | ||
| miR-183-3p | X | [13] | ||
| miR-183-5p | X | [13] | ||
| miR-184 | X | X | [128,162] | |
| miR-185 | X | X | [94,130] | |
| miR-185a | X | [168] | ||
| miR-185-5p | X | [13] | ||
| miR-186 | X | [29,47] | ||
| miR-188-5p | X | [169] | ||
| miR-190b | X | [132] | ||
| miR-191 | X | X | [14,128] | |
| miR-193 | X | [130] | ||
| miR-193a | X | [129] | ||
| miR-193a-3p | X | [109] | ||
| miR-193a-5p | X | [169] | ||
| miR-193b | X | [129] | ||
| miR-194 | X | X | [128,179,180] | |
| miR-195 | X | [118,169] | ||
| miR-196a-5p | X | [119] | ||
| miR-196b | X | [169] | ||
| miR-197 | X | [87] | ||
| miR-198 | X | [169] | ||
| miR-199a-5p | X | [169] | ||
| miR-199b-5p | X | [117,125,169] | ||
| miR-199b-3p | X | [125,169] | ||
| miR-199b | X | [121] | ||
| miR-200 | X | [181] | ||
| miR-200a | X | [29,114,121,125,127,128,129,169,177,178] | ||
| miR-200a-5p | X | [117] | ||
| miR-200a* | X | [121,169,178] | ||
| miR-200b | X | X | [29,114,121,125,129,169,174,177] | |
| miR-200b* | X | [125,169,178] | ||
| miR-200c | X | X | [29,40,121,125,126,128,129,169,177,178] | |
| miR-202 | X | X | [141,169] | |
| miR-202-3p | X | [67] | ||
| miR-203 | X | [121,125,128,129,169,177] | ||
| miR-203 | X | [142] | ||
| miR-204 | X | X | [10,54,182] | |
| miR-204-5p | X | [103] | ||
| miR-205 | X | [29,118,121,123,125,126,127,128,129,169,177,178] | ||
| miR-205-5p | X | [36] | ||
| miR-208a | X | [137] | ||
| miR-210 | X | [125,128,129,130,169,177] | ||
| miR-214 | X | [117,169] | ||
| miR-214* | X | [169] | ||
| miR-214-3p | X | [25] | ||
| miR-215 | X | [128] | ||
| miR-216b | X | [178] | ||
| miR-218 | X | [117] | ||
| miR-219-2 | X | [110] | ||
| miR-221 | X | [130] | ||
| miR-222 | X | X | [29,140,182] | |
| miR-222-3p | X | [170] | ||
| miR-223 | X | [29,126,128,140,169] | ||
| miR-224 | X | [169] | ||
| miR-299-3p | X | [169] | ||
| miR-299-5p | X | [169] | ||
| miR-301 | X | [51,128] | ||
| miR-302a-5p | X | [91] | ||
| miR-320a | X | [33] | ||
| miR-325 | X | [128] | ||
| miR-326 | X | X | [110,128] | |
| miR-328-3p | X | [119] | ||
| miR-330 | X | [128] | ||
| miR-330-3p | X | [169] | ||
| miR-331 | X | [54] | ||
| miR-331-3p | X | [69] | ||
| miR-335 | X | [39] | ||
| miR-337-3p | X | [119] | ||
| miR-337-5p | X | [117,169] | ||
| miR-340-5p | X | [33] | ||
| miR-361 | X | [66] | ||
| miR-363 | X | [129] | ||
| miR-368 | X | [129] | ||
| miR-369 | X | [126] | ||
| miR-370 | X | [117] | ||
| miR-371-5p | X | [169] | ||
| miR-373 | X | [97] | ||
| miR-375 | X | [169] | ||
| miR-376a | X | [125,169] | ||
| miR-376c | X | [117,125,169] | ||
| miR-377 | X | [117,169] | ||
| miR-379 | X | [169] | ||
| miR-381 | X | [125,169] | ||
| miR-382 | X | [146] | ||
| miR-409 | X | [126] | ||
| miR-410 | X | [121,125,169] | ||
| miR-411 | X | [127,169] | ||
| miR-421 | X | [125] | ||
| miR-423 | X | [126,130] | ||
| miR-424 | X | [125,126,169] | ||
| miR-424* | X | [125] | ||
| miR-424-3p | X | [117] | ||
| miR-425 | X | [126,169] | ||
| miR-429 | X | [114,117,121,125,129,169,177] | ||
| miR-431 | X | [125,126] | ||
| miR-432 | X | X | [125,129] | |
| miR-449 | X | [29,129] | ||
| miR-450a | X | [169] | ||
| miR-451 | X | [126] | ||
| miR-455-3p | X | [169] | ||
| miR-455-5p | X | [169] | ||
| miR-483-5p | X | [169] | ||
| miR-487b | X | [127] | ||
| miR-494 | X | [169] | ||
| miR-495 | X | [132] | ||
| miR-496 | X | [126] | ||
| miR-497 | X | [169] | ||
| miR-499 | X | [118] | ||
| miR-501-5p | X | [169] | ||
| miR-503 | X | [120,125,126,169] | ||
| miR-504 | X | [169] | ||
| miR-505* | X | [169] | ||
| miR-513a-5p | X | [169] | ||
| miR-513b | X | [169] | ||
| miR-516 | X | [126] | ||
| miR-516a-5p | X | [125] | ||
| miR-518c* | X | [169] | ||
| miR-519a | X | [177] | ||
| miR-520-5p | X | [161] | ||
| miR-522 | X | [161] | ||
| miR-526a | X | [161] | ||
| miR-542-3p | X | [125,169] | ||
| miR-542-5p | X | [117,125,169] | ||
| miR-543 | X | [183] | ||
| miR-557 | X | [169] | ||
| miR-564 | X | [169] | ||
| miR-572 | X | [127] | ||
| miR-575 | X | [169] | ||
| miR-589-5p | X | [13] | ||
| miR-596 | X | [125] | ||
| miR-601 | X | [136] | ||
| miR-605 | X | [125] | ||
| miR-610 | X | [125] | ||
| miR-614 | X | [125] | ||
| miR-616 | X | [54] | ||
| miR-622 | X | [127,169] | ||
| miR-623 | X | [169] | ||
| miR-625 | X | X | [54,135] | |
| miR-629* | X | [169] | ||
| miR-630 | X | X | [125,169] | |
| miR-632 | X | [125] | ||
| miR-638 | X | X | [22] | |
| miR-646 | X | [31] | ||
| miR-650 | X | [127] | ||
| miR-652 | X | [169] | ||
| miR-654-3p | X | [169] | ||
| miR-663 | X | X | [24,169] | |
| miR-758 | X | [117] | ||
| miR-760 | X | X | [125,169] | |
| miR-765 | X | [169] | ||
| miR-768-5p | X | [169] | ||
| miR-801 | X | [169] | ||
| miR-873 | X | [169] | ||
| miR-874 | X | [95] | ||
| miR-876 | X | [59] | ||
| miR-877 | X | [169] | ||
| miR-892b | X | [169] | ||
| miR-888 | X | [177] | ||
| miR-891a | X | [110] | ||
| miR-923 | X | [169] | ||
| miR-936 | X | [125] | ||
| miR-939 | X | [169] | ||
| miR-940 | X | [89] | ||
| miR-944 | X | [51,105] | ||
| miR-1202 | X | [108] | ||
| miR-1224 | X | [110] | ||
| miR-1224-5p | X | [169] | ||
| miR-1225-5p | X | [169] | ||
| miR-1226 | X | [169] | ||
| miR-1228 | X | [121] | ||
| miR-1247 | X | [117] | ||
| miR-1269 | X | [13] | ||
| miR-1271 | X | [184] | ||
| miR-1976 | X | [140] | ||
| miR-3170 | X | [140] | ||
| miR-3926-1 | X | [110] | ||
| miR-4461 | X | [27] | ||
| miR-4467 | X | [169] | ||
| miR-4758 | X | [28] | ||
| miR-5001-5p | X | [169] | ||
| miR-5787 | X | [108] | ||
| miR-6076 | X | [34] | ||
| miR-6511b | X | [27] | ||
| miR-6749-5p | X | [108] | ||
| miR-6950-5p | X | [169] |
X = when the miRNA is increased, decreased or if the methylation of miRNA’s loci is modified.