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. 2021 Mar 6;13(5):1130. doi: 10.3390/cancers13051130
5-FU 5-fluorouracile
aSMA Alpha-smooth-muscle actin
BMDCs Bone marrow-derived dendritic cells
BRAF Type B rapidly accelerated fibrosarcoma gene
CAFs Cancer-associated fibroblasts
CAM Cell-adhesion molecules
CAR Chimeric antigen receptor
CCL20 C-C Motif Chemokine Ligand 20
CCR6 C-C Motif Chemokine Receptor 6 ()
CD Cluster of Differentation
CEA Carcinoembryonic antigen
CMS Consensus molecular subtypes
CRC Colorectal cancer
CRISPR/Cas9 Clustered regularly interspaced short palindromic repeats/Cas9
CTLA-4 Cytotoxic T-Lymphocyte Antigen 4
CXCL5 C-X-C motif chemokine 5
CXCR4 C-X-C chemokine Receptor type 4
DCs Dendritic cells
dMMR Deficient mismatch repair
ECM Extracellular matrix
EGF Epidermal Growth Factor
FACS Fluorescence-activated cell sorting
FAP Fibroblast-activated protein
FDA Food and Drug Administration
FGFR1 Fibroblast growth factor receptor 1
FOLFIRI Folinic acid, 5-FU and irinotecan treatment
FSP1 Fibroblast-specific protein-1
HER2 Human EGF receptor 2 gene
HGF Hepatocyte Growth Factor
HIF-1 Hypoxia-inducible Factor 1 ()
ICAM Intercellular cell-adhesion molecules
IGF Insulin-like growth factor ())
ILs Interleukins
iNOS Induced nitric oxide synthase
KRAS Kirsten rat sarcoma viral gene
MARCO Macrophage receptor with collagenous structure
mCRC Metastasic colorectal cancer
MDSCs Myeloid-derived supressor cells
MHC Major histocompatibility complex
miRNAs MicroRNAs
MMP Matrix metalloproteinases
MMR Mismatch repair
mRNA Messenger RNA
MSI-H Microsatellite instability-high
NGS Next generation sequencing
NKs Natural killer cells
NOTCH1 Neurogenic locus Notch Homolog protein 1
NRAS Neuroblastoma rat sarcoma viral gene
NTRK Neurotrophic receptor tyrosine kinase gene
PD-1 Programmed Death-ligand 1
PDGF Platelet-derived growth factor
PDGFR Platelet-derived growth factor receptor
PIK3CA Phosphatidylinositol 3-kinase catalytic subunit alpha gene
PlGF Placental growth factor
pMMR-MSI-L Mismatch repair-proficient-microsatellite instability-low
PTEN Phosphatase and tensin homologue
RAS Rat sarcoma oncogene
ROS Reactive Oxygen Species
siRNAs Small interfering RNA
TAM Tumor-associated macrophage
TGF-β Transforming Growth Factor β
TIMP-1 Tissular inhibitor of metalloproteinases 1
TME Tumor microenvironment
TNFα Tumor Necrosis Factor α
TNM Tumor, Node, Metastases
TRAIL TNF-Related Apoptosis Inducing Ligand
Tsg101 Tumor susceptibility gene 101
VCAM Vascular cell-adhesion molecules
VEGF Vascular Endothelial Growth Factor