Table 1.
Characteristics of the population-based and breast cancer family-based studies.
| Controls (n = 2272) | Cases (n = 2228) | |
|---|---|---|
| Population-based study (MCCS) | ||
| Age at blood draw (median [IQR]) | 59.8 [52.7–65.0] | 60.3 [53.3–65.6] |
| Sex (female) | 919 (40%) | 901 (40%) |
| Country of birth | ||
| Australia/NZ | 1602 (70%) | 1571 (69%) |
| UK/Northern Europe | 161 (7%) | 156 (7%) |
| Italy | 311 (14%) | 297 (13%) |
| Greece | 198 (9%) | 204 (9%) |
| Smoking status | ||
| Never | 1154 (51%) | 1106 (49%) |
| Former | 854 (38%) | 888 (39%) |
| Current | 263 (11%) | 233 (10%) |
| BMI (kg/m2) | 26.4 [24.1–29.1] | 26.8 [24.4–29.7] |
| Alcohol consumption (g/day) | 4.3 [0.0–17.1] | 4.3 [0.0–17.1] |
| Alternate Healthy Eating Index 2010 | 63.5 [56.0–71.0] | 64.0 [56.5–71.5] |
| Family-based studies (ABCFR/kConFab) a | ||
| Sex (female) | 123 (100%) | 87 (100%) |
Abbreviations: MCCS: Melbourne Collaborative Cohort Study; ABCFR/kConFab: Australian Breast Cancer Family Registry and Kathleen Cuningham Foundation Consortium for research into Familial Breast Cancer; IQR: interquartile range; BMI: body mass index. a Of these 210 participants, 179 had sequencing data available.