Table 2.

Quigley–French Scale for androgen insensitivity syndrome (AIS) [30]. PAIS, partial androgen insensitivity, CAIS, complete androgen insensitivity.

Grade 1	Mild AIS (MAIS)	Male Genitals, Infertility
Grade 2	PAIS	male genitals but mildly ‘under-masculinized’, isolated hypospadias
Grade 3	PAIS	predominantly male genitals but more severely ‘under-masculinized’ (perineal hypospadias, small penis, cryptorchidism, i.e., undescended testes, and/or bifid scrotum)
Grade 4	PAIS	ambiguous genitals, severely ‘under-masculinized’ (a phallic structure that is indeterminate between a penis and a clitoris)
Grade 5	PAIS	essentially female genitals (including separate urethral and vaginal orifices, mild clitoromegaly, i.e., enlarged clitoris)
Grade 6	CAIS	female genitals with pubic/underarm hair
Grade 7	CAIS	female genitals