Table 2.
Studies that investigated erectile dysfunction (ED) and reduced libido prevalence in HIV patients.
| Study | n | Age | MSM (%) | IV Drug Use (%) | Reduced SD (%) | ED (%) | ED Diagnostic Tool |
|---|---|---|---|---|---|---|---|
| Lallemand et al. (2002) [89] | 156 | 40.5 ± 7.7 * | 100 | NR | 89 | 86 | IIEF-15 |
| Ende et al. (2006) [87] | 118 | 41 (28–67) § | 70 | 7 | NA | 74 | IIEF-5 |
| Asboe et al. (2007) [69] | 668 | - | 73 | - | 24 | 33 | IIEF-15 |
| Crum-Cianflone et al. (2007) [90] | 285 | 39 (19–72) * | NR | 8 | NR | 61.4 | IIEF-15 |
| Guaraldi et al. (2007) [88] | 357 | 45 (45–46) * | 43 | NR | NR | 53.2 | IIEF-15 |
| Moreno-Pérez et al. (2010) [91] | 90 | 42 ± 8.2 * | 80 | 0 | NR | 53.4 | IIEF-15 |
| Rochira et al. (2011) [79] | 247 | 45 (20–69) § | NR | NR | 65.2 | 53.4 | IIEF-15 |
| Guaraldi et al. (2012) [45] | 133 | 49 * | 52 | 26 | NR | 59.3 | IIEF-15 |
| Zona et al. (2012) ¶ [11] | 444 | 44.8 ± 5.9 * | 43 | 34 | NR | 54.5 | IIEF-15 |
| Hart et al. (2012) ¶ [92] | 1340 | 48 (42–54) § | 100 | NR | NR | 21 | IIEF-MSM |
| Vansintejan et al. (2013) [93] | 72 | 41 ± 10 * | 100 | NR | 15 | 56 | IIEF-5 ** |
| Wang et al. (2013) [95] | 4064 | 46 § | NR | NR | NR | 24 | IIIEF-15 ‡‡ |
| Perez et al. (2013) [75] | 158 | 46 * | 58.2 | NR | NA | 67.1 | IIEF-5 |
| Romero-Velez et al. (2014) [94] | 109 | 39.9 ± 8.8 * | 70.6 | NR | NR | 65 | IIEF-15 |
| Hart et al. (2015) ¶ [101] | 619 | 47.3 ± 8.9 * | 100 | NR | NR | 24.7 | IIEF-MSM |
| Pinzone et al. (2015) [96] | 109 | 47 (40–52) § | 54 | 20.2 | NR | 65 | IIEF-15 |
| Fumaz et al. (2017) [97] | 501 | 42 (35–48) § | 75.8 | NR | NA | 58.4 | IIEF-5 |
| Aghahowa et al. (2017) [98] | 217 | 37.9 ± 9.9 * | 63.6 | 9.5 | NR | 82.3 | IIEF-15 |
| Dijkstra et al. (2018) ¶ [73] | 399 | 53.6 (48.6–60.0) § | 100 | 2 | 7 | 13 | IIEF-15 ‡‡ |
| Veras Gomes et al. (2019) [99] | 134 | 44.7 ± 11.0 * | 40 | NR | NR | 22 | IIEF-15 |
| Bernal et al. (2019) [100] | 139 | 45.22 ± 10.47 * | 55.6 | 3.7 | NA | 61.2 | IIEF-5 |
* Mean ± standard deviation § Median ± interquartile range All studies were cross-sectional, non-controlled except for ¶ prospective controlled study. ** Web-based self-filled International Index of Erectile Function-5 (IIEF-5). ‡‡ In these studies, the authors used a not-validated modified version of IIEF-15. Abbreviations: IIEF, International Index of Erectile Function; ED, erectile dysfunction; HAART, highly active antiretroviral therapy; IV, intravenous; MSM, men who have sex with men; NA, not applicable; NR, not reported; SD, sexual desire.