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. 2021 Mar 4;22(5):2562. doi: 10.3390/ijms22052562

Figure 4.

Figure 4

Serial measurement of expressed allele burden (EAB, cDNA) and variant allele fraction (VAF, gDNA) on midostaurin. Irrespective of the cohorts (cohort A: EAB/VAF ≤ 2, (A,B); cohort B: EAB/VAF > 2, (C,D)), the changes of KIT EAB and VAF nearly paralleled each other.