Table 2.
Epitopes of structural proteins for each Human Leukocyte Antigen (HLA) allele *.
| MHC Class I | MHC Class II | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Allele | Spike Protein | Envelope Protein | Membrane Protein | Nucleo Capsid Protein | Allele | Spike Protein | Envelope Protein | Membrane Protein | Nucleo-Capsid Protein |
| HLA-A*01:01 | 6 | 1 | 3 | 1 | HLA-DPA1*01:03/DPB1*02:01 | 73 | 8 | 22 | 8 |
| HLA-A*02:01 | 36 | 11 | 17 | 2 | HLA-DPA1*02:01/DPB1*01:01 | 70 | 5 | 21 | 10 |
| HLA-A*02:03 | 75 | 13 | 19 | 7 | HLA-DPA1*02:01/DPB1*05:01 | 22 | 2 | 9 | 1 |
| HLA-A*02:06 | 74 | 13 | 19 | 11 | HLA-DPA1*03:01/DPB1*04:02 | 46 | 4 | 14 | 4 |
| HLA-A*03:01 | 22 | 2 | 4 | 5 | HLA-DQA1*01:01/DQB1*05:01 | 20 | 0 | 7 | 2 |
| HLA-A*11:01 | 41 | 2 | 9 | 9 | HLA-DQA1*01:02/DQB1*06:02 | 71 | 5 | 14 | 15 |
| HLA-A*23:01 | 25 | 2 | 11 | 3 | HLA-DQA1*03:01/DQB1*03:02 | 7 | 0 | 1 | 2 |
| HLA-A*24:02 | 19 | 0 | 8 | 2 | HLA-DQA1*04:01/DQB1*04:02 | 9 | 0 | 2 | 3 |
| HLA-A*26:01 | 8 | 1 | 2 | 2 | HLA-DQA1*05:01/DQB1*02:01 | 32 | 0 | 4 | 5 |
| HLA-A*30:01 | 53 | 5 | 19 | 24 | HLA-DQA1*05:01/DQB1*03:01 | 82 | 2 | 11 | 31 |
| HLA-A*30:02 | 25 | 3 | 8 | 4 | HLA-DRB1*01:01 | 158 | 10 | 27 | 30 |
| HLA-A*31:01 | 34 | 4 | 14 | 14 | HLA-DRB1*03:01 | 37 | 2 | 8 | 5 |
| HLA-A*32:01 | 26 | 4 | 9 | 6 | HLA-DRB1*04:01 | 106 | 6 | 18 | 21 |
| HLA-A*33:01 | 17 | 1 | 11 | 5 | HLA-DRB1*04:05 | 101 | 6 | 20 | 20 |
| HLA-A*68:01 | 49 | 3 | 13 | 11 | HLA-DRB1*07:01 | 123 | 9 | 22 | 14 |
| HLA-A*68:02 | 57 | 8 | 11 | 8 | HLA-DRB1*08:02 | 68 | 6 | 18 | 14 |
| HLA-B*07:02 | 10 | 0 | 3 | 5 | HLA-DRB1*09:01 | 124 | 7 | 22 | 22 |
| HLA-B*08:01 | 15 | 1 | 3 | 4 | HLA-DRB1*11:01 | 77 | 5 | 19 | 15 |
| HLA-B*15:01 | 48 | 5 | 11 | 7 | HLA-DRB1*12:01 | 46 | 6 | 18 | 6 |
| HLA-B*35:01 | 42 | 5 | 5 | 8 | HLA-DRB1*13:02 | 103 | 8 | 20 | 15 |
| HLA-B*40:01 | 9 | 1 | 1 | 0 | HLA-DRB1*15:01 | 98 | 8 | 23 | 17 |
| HLA-B*44:02 | 6 | 0 | 1 | 1 | HLA-DRB3*01:01 | 41 | 2 | 6 | 4 |
| HLA-B*44:03 | 6 | 0 | 1 | 1 | HLA-DRB3*02:02 | 53 | 5 | 9 | 8 |
| HLA-B*51:01 | 3 | 0 | 1 | 1 | HLA-DRB4*01:01 | 93 | 8 | 24 | 17 |
| HLA-B*53:01 | 16 | 0 | 6 | 4 | HLA-DRB5*01:01 | 91 | 5 | 20 | 22 |
| HLA-B*57:01 | 13 | 0 | 5 | 3 | |||||
| HLA-B*58:01 | 30 | 1 | 10 | 4 | |||||
| Sum | 765 | 86 | 224 | 152 | 1751 | 119 | 379 | 311 | |
* Summary numbers are given for each allele. The detailed information about the binding capacity and epitope position is listed in Table S3.