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. 2021 Mar 6;26(5):1433. doi: 10.3390/molecules26051433

Table 4.

Plasma pharmacokinetic variables of setipiprant in healthy subjects after administration of a single 500 mg dose of setipiprant as a capsule (n = 20) or tablet (n = 20) (values were obtained from [79]).

Variable Capsule a Tablet a Tablet: Capsule b
Cmax, µg/mL 6.44 (5.46–7.58) 6.04 (4.72–7.74) 0.94 (0.79–1.12)
tmax, h 3.00 (1.50–5.00) 3.50 (1.00–5.00) 0.00 (−0.50–1.00)
t1/2, h 11.12 (9.76–12.67) 11.40 (10.54–12.34) 1.03 (0.93–1.13)
AUC0−∞, µg∙h/mL 31.50 (26.52–37.40) 31.88 (26.54–38.31) 1.01 (0.92–1.12)

a Values indicate geometric means (95% CIs), except for tmax, for which median and range are presented. b Values indicate ratio of geometric means (90% CIs), except for tmax, for which difference of medians (90% CIs) is presented.