Table 3.
Effect of post-translational modifications on isoelectric point of Zyxin family proteins.
| Protein | pI | Number of Sites for PTM | ||||||
|---|---|---|---|---|---|---|---|---|
| Native 1 | Post PTM *,2 | Phosphorylation | Acety- Lation * |
Ubiquity- Lation * |
Monomethy- Lation * |
Dimethy- Lation * |
Caspase Cleavage Sites * | |
| Zyxin | 6.22 | 6.12–3.17 | 66 | 5 | 4 | 3 | 2 | 1 |
| LimD1 | 6.20 | 6.12–3.85 | 65 | - | 8 | 4 | - | - |
| Ajuba | 6.86 | 6.63–4.63 | 30 | - | 2 | 1 | - | - |
| LPP | 7.18 | 6.89–2.84 | 83 | 3 | 5 | 1 | 1 | - |
| WTIP | 8.53 | 8.36–6.22 | 11 | - | - | - | - | - |
| FBLIM1 | 5.71 | 5.60–4.96 | 9 | 1 | - | - | - | - |
| TRIP6 | 7.19 | 6.89–3.61 | 56 | - | - | 22 | 4 | - |
* = Data obtained from PhosphositePlus. 1 = Calculated from ProtParam; 2 = Range is from single phosphorylation to maximum number of phosphorylation.