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The secondary and tertiary structures of Mango RNA aptamer. (A) The secondary structure of Mango RNA aptamer showing the three G-quadruplex regions stacked in three tiers (T1, T2, and T3), where T3 serves as the binding site for TO1-biotin fluorophore [82,83]. (B) A cartoon representation of the tertiary structure of Mango RNA aptamer (PDB ID: 6C63) [84].
