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. Author manuscript; available in PMC: 2021 Jul 1.
Published in final edited form as: Psychopharmacology (Berl). 2020 Apr 20;237(7):1973–1987. doi: 10.1007/s00213-020-05512-0

Fig. 3.

Fig. 3

Consequences of genetic and pharmacological disruption of norepinephrine transmission on marble burying. a Compared to Dbh +/− controls (n = 15), Dbh −/− (n = 13) mice buried fewer marbles. b In control mice, PROP (10 mg/kg) was ineffective, but PRAZ (0.5 mg/kg), co-administration of PRAZ + PROP, or GUAN (0.3 mg/kg) reduced MB compared to VEH (n = 10, repeated measures). c Representative images of MB cages from Dbh +/− mice treated with VEH compared to GUAN. ***p < 0.001, *p < 0.05.