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Formation of exosomes and uptake into target cells. Early endosomes are formed by endocytosis and they transition to late endosomes. These are called multivesicular bodies (MVBs), with intraluminal membrane vesicles (ILVs). ILVs that are released from MVBs into the extracellular space are called exosomes. Released exosomes are taken up by the target cells through endocytosis, interactions with receptors on the cell membrane, or direct fusion with the cell membrane.
