| 3′UTR | three prime untranslated region |
| ACI | autologous chondrocyte implantation |
| ACLT | anterior cruciate ligament transection |
| ADAMTS5 | a disintegrin and metalloproteinase with thrombospondin motifs 5 |
| AKT | AKT serine/threonine kinase 1 |
| ALIX | ALG-2-interacting protein X |
| ATG4B | autophagy related 4B cysteine peptidase |
| CAP | chondrocyte-affinity peptide |
| CD | cluster of differentiation |
| DACT1 | dishevelled binding antagonist of beta catenin 1 |
| DDS | drug delivery system |
| DMM | destabilization of the medial meniscus |
| DMOAD | disease-modifying OA drugs |
| DNA | deoxyribonucleic acid |
| ECM | extracellular matrix |
| ESCRT | endosomal sorting complexes required for transport |
| EV | extracellular vesicle |
| GelMA | gelatin methacrylate |
| GSK-3β | glycogen synthase kinase 3 beta |
| hBMSC | human bone marrow-derived MSC |
| HDAC | histone deacetylase |
| Hsp | heat shock protein |
| hUC | human umbilical cord |
| IL-1β | interleukin-1 beta |
| ILV | intraluminal membrane vesicle |
| IPFP | infrapatellar fat pad |
| ISEV | International Society for Extracellular Vesicles |
| Lamp2b | lysosome-associated membrane glycoprotein 2b |
| lncRNA | long noncoding RNA |
| MCH | major histocompatibility complex |
| MCS | mesenchymal stem cell |
| miRNA | microRNA |
| MISEV | Minimal Information for Studies of Extracellular Vesicles |
| MMP13 | matrix metalloproteinase 13 |
| mTOR | mammalian target of rapamycin |
| MVB | multivesicular body |
| NSAID | non-steroidal anti-inflammatory drugs |
| OAK | osteoarthritis of knee |
| PCGEM1 | prostate-specific transcript 1 |
| PHC | primary human chondrocytes |
| PTEN | phosphatase and tensin homolog deleted from chromosome 10 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 |
| RA | rheumatoid arthritis |
| RNA | ribonucleic acid |
| siRNA | small interfering RNA |
| SMSC | synovium-derived MSC |
| SOX9 | SRY-box transcription factor 9 |
| SRDDS | sustained release drug delivery system |
| TGF-β1 | transforming growth factor beta 1 |
| TKA | total knee arthroplasty |
| TLR | Toll-like receptor |
| TSG101 | tumor susceptibility gene 101 |
| WNT5A | Wnt family member 5A |
| YAP | Yes-associated protein |