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. 2021 Mar 5;22(5):2607. doi: 10.3390/ijms22052607
aa Amino Acid(s)
ad Autosomal Dominant
AFP Alpha Fetal Protein
Cas CRISPR-associated
COS7 CV-1 Origin Sv40
CNV Copy Number Variant
CRISPR Clustered Regularly Interspaced Short Palindromic Repeats
CRX Cone-Rod Homeobox
DBD DNA Binding Domain
DSB Double-Strand Break
EGFP Enhanced Green Fluorescent Protein
ESCS Enhanced S Cone Syndrome
GFAP Glial Fibrillary Acidic Protein
gRNA Guide RNA
HDR Homologous-Directed Repair
HEK293 Human Embryonic Kidney
indels Insertions/deletions
iPSC induced Pluripotent Stem Cell
IRD Inherited Retinal Dystrophies
KLF4 Kruppel-Like Factor
LBD Ligand Binding Domain
LIN28A Lin-28 Homolog A
NANOG Nanog Homeobox
NES Nuclear Export Signal
NHEJ Non-Homologous End Joining
NLS Nuclear Localization Signal
NMD Nonsense-Mediated Decay
NR1D1 Nuclear Receptor Subfamily 1 Group D Member 1
NR2E3 Nuclear Receptor Subfamily 2 Group E Member
NRL Neural Retina Leucine Zipper
OCT3/4 Octamer Binding Transcription Factor
OTX2 Orthodenticle Homeobox 2
PAM Protospacer Adjacent Motif
PTC Premature Termination Codon
RP Retinitis Pigmentosa
SeV Sendai Virus
SMA Smooth Muscle Actin
SOX2 SRY-Box Transcription Factor 2
Sp Streptococcus Pyogenes
T7E1 T7 Endonuclease 1
WT Wild type