aa |
Amino Acid(s) |
ad |
Autosomal Dominant |
AFP |
Alpha Fetal Protein |
Cas |
CRISPR-associated |
COS7 |
CV-1 Origin Sv40 |
CNV |
Copy Number Variant |
CRISPR |
Clustered Regularly Interspaced Short Palindromic Repeats |
CRX |
Cone-Rod Homeobox |
DBD |
DNA Binding Domain |
DSB |
Double-Strand Break |
EGFP |
Enhanced Green Fluorescent Protein |
ESCS |
Enhanced S Cone Syndrome |
GFAP |
Glial Fibrillary Acidic Protein |
gRNA |
Guide RNA |
HDR |
Homologous-Directed Repair |
HEK293 |
Human Embryonic Kidney |
indels |
Insertions/deletions |
iPSC |
induced Pluripotent Stem Cell |
IRD |
Inherited Retinal Dystrophies |
KLF4 |
Kruppel-Like Factor |
LBD |
Ligand Binding Domain |
LIN28A |
Lin-28 Homolog A |
NANOG |
Nanog Homeobox |
NES |
Nuclear Export Signal |
NHEJ |
Non-Homologous End Joining |
NLS |
Nuclear Localization Signal |
NMD |
Nonsense-Mediated Decay |
NR1D1 |
Nuclear Receptor Subfamily 1 Group D Member 1 |
NR2E3 |
Nuclear Receptor Subfamily 2 Group E Member |
NRL |
Neural Retina Leucine Zipper |
OCT3/4 |
Octamer Binding Transcription Factor |
OTX2 |
Orthodenticle Homeobox 2 |
PAM |
Protospacer Adjacent Motif |
PTC |
Premature Termination Codon |
RP |
Retinitis Pigmentosa |
SeV |
Sendai Virus |
SMA |
Smooth Muscle Actin |
SOX2 |
SRY-Box Transcription Factor 2 |
Sp |
Streptococcus Pyogenes
|
T7E1 |
T7 Endonuclease 1 |
WT |
Wild type |