Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Crystal structures of Btk in complex with inhibitors. Secondary structure cartoons of the catalytic domain of Btk in complex with (A) Ibrutinib (PDB entry code 5P9J), (B) Fenebrutinib (PDB entry code 5VFI) and (C) Remibrutinib (PDB entry code 6TFP). Highlighted are Cys481 (orange circle) and Tyr551 (red circle). Snap shots were visualized using the web-based NGL viewer.
