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. 2021 Mar 4;22(5):2576. doi: 10.3390/ijms22052576

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of EMPA on metabolic parameters in PCOS. (A–C) Effect of EMPA on (A) fasting plasma insulin, (B) fasting plasma glucose, and (C) insulin sensitivity (QUICKI). (D–H) Effect of EMPA on (D) hemoglobin A1c (HbA1c), (E) fasting plasma total cholesterol, (F) fasting plasma low-density lipoprotein cholesterol (LDL-Chol), (G) fasting plasma high-density lipoprotein cholesterol (HDL-Chol), (H) fasting plasma triglycerides, (I) plasma leptin, and (J) serum DHT. Data are expressed as mean ± SEM. Data were analyzed by two-way ANOVA followed by Tukey post-hoc tests. Significant interaction was observed only for HDL-Chol. * p < 0.05. n = 7–10 per group.